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Models

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Mice

Aadacl3-Flox

Strain Name：C57BL/6Smoc-Aadacl3em1(flox)Smoc
Strain State：Repository Live | Cat. NO.：NM-CKO-253851

These mice carry loxP sites flanking exon 2-3 of Aadacl3 gene. When crossed with a Cre recombinase-expressing strain, this strain is useful in eliminating tissue-specific conditional expression of Aadacl3 gene.

Mice

Apc-L850X

Strain Name：C57BL/6Smoc-Apcem1(L850X)Smoc
Strain State：Repository Live | Cat. NO.：NM-KI-200001
Validation Data：Presence

Familial adenomatous polyposis (FAP) is a heritable condition in which affected individuals develop benign intestinal polyps. Often, polyps progress to colorectal carcinomas later in life. The mutation of C57BL/6-Apcem1(L850X)Smoc(NM-KI-200001) strain of SMOC refers to the ApcMin model (Jax: 002020 ), a useful model to study intestinal adenomas. The C57BL/6-Apcem1(L850X)Smoc strain is highly susceptible to spontaneous intestinal adenoma formation and can be used as a research model for human FAP. These mice carry a p.L850X mutation of Apc gene.

Mice

Abcb8-Flox

Strain Name：C57BL/6Smoc-Abcb8em1(flox)Smoc
Strain State：Repository Live | Cat. NO.：NM-CKO-253536

These mice carry loxP sites flanking exon 3-6 of Abcb8 gene. When crossed with a Cre recombinase-expressing strain, this strain is useful in eliminating tissue-specific conditional expression of Abcb8 gene.

Mice

A26c3-Flox

Strain Name：C57BL/6Smoc-A26c3em1(flox)Smoc
Strain State：Developing | Cat. NO.：TBD

These mice carry loxP sites flanking target exons of A26c3 gene. When crossed with a Cre recombinase-expressing strain, this strain is useful in eliminating tissue-specific conditional expression of A26c3 gene.

Mice

Aacs-Flox

Strain Name：C57BL/6Smoc-Aacsem1(flox)Smoc
Strain State：Repository Live | Cat. NO.：NM-CKO-253839

These mice carry loxP sites flanking exon 2 of Aacs gene. When crossed with a Cre recombinase-expressing strain, this strain is useful in eliminating tissue-specific conditional expression of Aacs gene.

Mice

Aak1-Flox

Strain Name：C57BL/6Smoc-Aak1em1(flox)Smoc
Strain State：Repository Live | Cat. NO.：NM-CKO-253921

These mice carry loxP sites flanking exon 2 of Aak1 gene. When crossed with a Cre recombinase-expressing strain, this strain is useful in eliminating tissue-specific conditional expression of Aak1 gene.

Mice

Aadat-Flox

Strain Name：C57BL/6Smoc-Aadatem1(flox)Smoc
Strain State：Repository Live | Cat. NO.：NM-CKO-253922

These mice carry loxP sites flanking exon 2 of Aadat gene. When crossed with a Cre recombinase-expressing strain, this strain is useful in eliminating tissue-specific conditional expression of Aadat gene.

Mice

Aadacl4fm1-Flox

Strain Name：C57BL/6Smoc-Aadacl4fm1em1(flox)Smoc
Strain State：Repository Live | Cat. NO.：NM-CKO-253852

These mice carry loxP sites flanking exon 2 of Aadacl4fm1 gene. When crossed with a Cre recombinase-expressing strain, this strain is useful in eliminating tissue-specific conditional expression of Aadacl4fm1 gene.

Mice

Aadacl4fm2-Flox

Strain Name：C57BL/6Smoc-Aadacl4fm2em1(flox)Smoc
Strain State：Repository Live | Cat. NO.：NM-CKO-253926

These mice carry loxP sites flanking exon 2 of Aadacl4fm2 gene. When crossed with a Cre recombinase-expressing strain, this strain is useful in eliminating tissue-specific conditional expression of Aadacl4fm2 gene.

Mice

Aadacl2fm2-Flox

Strain Name：C57BL/6Smoc-Aadacl2fm2em1(flox)Smoc
Strain State：Repository Live | Cat. NO.：NM-CKO-253920

These mice carry loxP sites flanking exon 2 of Aadacl2fm2 gene. When crossed with a Cre recombinase-expressing strain, this strain is useful in eliminating tissue-specific conditional expression of Aadacl2fm2 gene.

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