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Models

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Mice

Ncr1-IRES-DTRGFP(BALB/c)

Strain Name：BALB/cAnSmoc-Ncr1em1(IRES-DTREGFP)Smoc
Strain State：Developing | Cat. NO.：NM-KI-200180

A IRES-DTREGFP expression cassette was knocked into the Ncr1 gene stop codon site.

Mice

Lepr-g.G109052T

Strain Name：B6.129S-Leprtm1Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-KI-00001

A point mutation was introduced to exon 19 (c.109052 G>T) via a recombineering strategy. Homozygous mutants are hyperphagic, low-activity, poorly cold-adapted, sterile and have enhanced fat conversion.

Mice

P2ry1-IRES-Cre

Strain Name：C57BL/6Smoc-P2ry1em1(Ires-iCre-pA)Smoc
Strain State：Repository Live | Cat. NO.：NM-KI-200121

A Ires-iCre-pA expression cassette was knocked into the P2ry1 gene stop codon site.

Mice

Fos-2A-tdTomato

Strain Name：C57BL/6Smoc-Fosem2(2A-tdTomato)Smoc
Strain State：Repository Live | Cat. NO.：NM-KI-190048

A 2A-tdTomato expression cassette was knocked into the Fos gene stop codon site.

Mice

Cdh1-2A-DreERT2

Strain Name：C57BL/6Smoc-Cdh1em3(2A-DreERT2)Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-KI-190031

A 2A-DreERT2 expression cassette was knocked into the Cdh1 gene stop codon site via CRISPR/Cas mediated recombination.

Mice

Krt14-KO

Strain Name：C57BL/6Smoc-Krt14em1Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-KO-00072

A total of 384 nucleotides were removed, including 5'UTR, ATG the start codon and part of the coding sequece.

Mice

Ly6g-2A-DreERT2

Strain Name：C57BL/6Smoc-Ly6gem1(2A-DreERT2)Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-KI-190036

A 2A-DreERT2 expression cassette was knocked into the Ly6g gene stop codon site via CRISPR/Cas mediated recombination.

Mice

Procr-2A-tdTomato

Strain Name：C57BL/6Smoc-Procrem2(2A-tdTomato)Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-KI-190051

A 2A-tdTomato expression cassette was knocked into the Procr gene stop codon site.

Mice

Mdm4-C462A

Strain Name：B6;129S-Mdm4tm1Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-KI-00007

A point mutant at exon 12 was recombined to create a Mdm4 gene mutant mice.

Mice

H11-pThy1-hPSEN1-IRES-tdTomato

Strain Name：C57BL/6Smoc-Igs2em1(pThy1-PSEN1-IRES-tdTomato-WPRE-pA)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-KI-18049

A Thy1 promoter-PSEN1-IRES-tdTomato-WPRE-polyA cassette was knocked into the Igs2 locus (Hipp11 or H11; an intergenic region on chromosome 11 [cytoband A1 at ~3cM between the Eif4enif1 and Drg1 loci] reported to support high-level global gene expression in conjunction with the CAG (CAGGS) promoter and a higher rate of mitotic/interchromosomal recombination compared to Gt(ROSA)26Sor) .

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