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Mice

Foxp3-IRES-Luc-2A-tdTomato

Strain Name：C57BL/6Smoc-Foxp3em1(IRES-Luci-2A-tdTomato)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-KI-200065

A IRES-luci-2A-tdTomato expression cassette was knocked into the Foxp3 gene stop codon site.

Mice

Isl1-Dre

Strain Name：C57BL/6Smoc-Isl1em1(Dre-Wpre-polyA)Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-KI-200177

A Dre-Wpre-polyA expression cassette was knocked into the Isl1 gene start codon site.

Mice

Etv1-CreERT2

Strain Name：C57BL/6Smoc-Etv1em1(CreERT2-SV40-pA)Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-KI-200105

A CreERT2 expression cassette was knocked into the Etv1 gene start codon site. ETV1 expression is enriched in fast conduction tissues of embryonic and adult mammalian hearts. And ETV1 expression is upregulated in the atrial tissue of patients with permanent atrial fibrillation. Etv-CreERT2 mice can be applied to heart disease research. ETV1 is also expressed in retinal ganglion cells of adult mice, and the mouse model can be used to study how retinal ganglion cells contribute to visual processing in the brain.

Mice

Pax7-IRES-Cre

Strain Name：C57BL/6Smoc-Pax7em1(IRES-iCre)Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-KI-200120

A IRES-iCre expression cassette was knocked into the Pax7 gene stop codon site. Pax7 is expressed in myogenic progenitor cells. Pax7 is essential for the myogenic potential, survival, and proliferation of myogenic progenitors. When crossed with a strain carrying a gene flanked by loxP sites, the flanked gene will be removed in cells expressing Pax7.

Mice

Ptf1a-CreERT2

Strain Name：C57BL/6Smoc-Ptf1aem1(CreERT2-WPRE-pA)Smoc
Strain State：Repository Live | Cat. NO.：NM-KI-200118

A CreERT2-WPRE-pA expression cassette was knocked into the Ptf1a gene start codon site.

Mice

Myf5-Cre

Strain Name：C57BL/6Smoc-Myf5em1(Cre-WPRE-polyA)Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-KI-200147

A Cre-WPRE-polyA expression cassette was knocked into the Myf5 gene start codon site. Myogenic factor 5 (Myf5) belongs to the MRF family transcription factors that regulate myogenesis. It is expressed in the skeletal muscle and satellite cells. Severe loss of skeletal muscle following ablation of Myf5-expressing progenitors. This strain is useful in studying the differentiation of skeletal muscle.

Mice

Mc4r-2A-Cre

Strain Name：C57BL/6Smoc-Mc4rem1(T2A-Cre)Smoc
Strain State：Repository Live | Cat. NO.：NM-KI-200220

A T2A-Cre expression cassette was knocked into the Mc4r gene stop codon site.

Mice

Il22-Cre

Strain Name：C57BL/6Smoc-Il22em1(Linker-iCre-PolyA(SV40)Smoc
Strain State：Repository Live | Cat. NO.：NM-KI-200167

A Linker-iCre-PolyA expression cassette was knocked into the Il22 gene start codon site.

Mice

Calb1-2A-GFPCre

Strain Name：C57BL/6Smoc-Calb1em1(2A-EGFP-Cre)Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-KI-200141

A 2A-EGFP-Cre expression cassette was knocked into the Calb1 gene stop codon site. Calb1 is highly expressed in the brain. When crossed with a strain carrying a gene flanked by loxP sites, the flanked gene will be removed in cells expressing Cre. This strain is useful in studying many neurobehavioral diseases such as spatial learning and circadian rhythm interference. It has been reported that the incidence of many diseases may be different between genders.

Mice

Crh-IRES-Cre

Strain Name：C57BL/6Smoc-Crhem1(IRES-iCre-pA)Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-KI-200104

A IRES-iCre-pA expression cassette was knocked into the Crh gene stop codon site. This strain exhibits ectopic expression, and its expression profile requires validation.

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