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Mice

Slc6a11-CreERT2

Strain Name：C57BL/6Smoc-Slc6a11em1(CreERT2-polyA(SV40)Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-KI-200130
Validation Data：Presence

A CreERT2-polyA expression cassette was knocked into the Slc6a11 gene start codon site. Slc6a11 encodes GAT3 (Gabt4), a sodium-dependent transporter that uptakes the inhibitory neurotransmitter gamma-aminobutyric acid (GABA), which ends the GABA neurotransmission. When Slc6a11-CreERT2 mice are bred with mice containing loxP-flanked sequence, tamoxifen-inducible, Cre-mediated recombination will result in deletion of the floxed sequences in SLC6A11positive cells. Defects in Slc6a11 may result in epilepsy or behavioral and intellectual defects.

Mice

Cd68-IRES-Cre

Strain Name：C57BL/6Smoc-Cd68em1(IRES-Cre)Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-KI-200161

A IRES-Cre expression cassette was knocked into the Cd68 gene stop codon site.

Mice

Il17a-2A-CreERT2

Strain Name：C57BL/6Smoc-Il17aem1(2A-CreERT2)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-KI-00059

A 2A-Cre cassette was inserted before stop codon of mouse Il17a gene which is known as a T cell marker.

Mice

Tert-CreERT2-2A-EGFP

Strain Name：C57BL/6Smoc-Tertem1(CreERT2-2A-GFP-WPRE-PA)Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-KI-18037
Validation Data：Presence

A CreERT2-2A-GFP-WPRE-PA expression cassette was knocked into the Telt gene start codon site by homologous recombination.

Mice

Foxp3-DreERT2

Strain Name：C57BL/6Smoc-Foxp3em5(IRES-DreER)Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-KI-200198

A IRES-DreER expression cassette was knocked into the Foxp3 gene stop codon site.

Mice

Il1a-Luc-2A-EGFP

Strain Name：C57BL/6Smoc-Il1aem1(Luc-eGFP)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-KI-00009
Validation Data：Presence

A Luciferase-2A-EGFP-pA cassette was inserted after ATG the start codon.

Mice

Pax7-IRES-Cre

Strain Name：C57BL/6Smoc-Pax7em1(IRES-iCre)Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-KI-200120
Validation Data：Presence

A IRES-iCre expression cassette was knocked into the Pax7 gene stop codon site. Pax7 is expressed in myogenic progenitor cells. Pax7 is essential for the myogenic potential, survival, and proliferation of myogenic progenitors. When crossed with a strain carrying a gene flanked by loxP sites, the flanked gene will be removed in cells expressing Pax7.

Mice

Myf5-Cre

Strain Name：C57BL/6Smoc-Myf5em1(Cre-WPRE-polyA)Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-KI-200147
Validation Data：Presence

A Cre-WPRE-polyA expression cassette was knocked into the Myf5 gene start codon site. Myogenic factor 5 (Myf5) belongs to the MRF family transcription factors that regulate myogenesis. It is expressed in the skeletal muscle and satellite cells. Severe loss of skeletal muscle following ablation of Myf5-expressing progenitors. This strain is useful in studying the differentiation of skeletal muscle.

Mice

Mc4r-2A-Cre

Strain Name：C57BL/6Smoc-Mc4rem1(T2A-Cre)Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-KI-200220
Validation Data：Presence

A T2A-Cre expression cassette was knocked into the Mc4r gene stop codon site.

Mice

Mcpt8-2A-CreERT2

Strain Name：C57BL/6Smoc-Mcpt8em1(2A-CreERT2-WPRE-polyA)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-KI-200006
Validation Data：Presence

A 2A-CreERT2-WPRE-polyA expression cassette was knocked into the Mcpt8 gene stop codon site.

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