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Mice

Cd19-IRES-DTRGFP

Strain Name:C57BL/6Smoc-Cd19em2(IRES-DTREGFP)Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-KI-190042

A IRES-DTREGFP expression cassette was knocked into the Cd19 gene stop codon site.

Mice

Pdcd1-DTR-2A-tdTomato

Strain Name:C57BL/6Smoc-Pdcd1em1(DTR-2A-tdTomato-WPRE-pA)Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-KI-200225

A DTR-2A-tdTomato-WPRE-pA expression cassette was knocked into the Pdcd1 gene start codon site.

Mice

Krt14-CreERT2

Strain Name:C57BL/6Smoc-Krt14em2(CreERT2-Wpre-polyA)Smoc
Strain State:Repository Live | Cat. NO.:NM-KI-190024

A CreERT2-Wpre-polyA expression cassette was knocked into initiation codon ATG site of the Krt14 gene.

Mice

Calb2-IRES-Cre

Strain Name:C57BL/6Smoc-Calb2em1(IRES-iCre-SV40-pA)Smoc
Strain State:Sperm cryopreservation | Cat. NO.:NM-KI-200102

A IRES-iCre expression cassette was knocked into the Calb2 gene stop codon site. Calb2 gene encodes calbindin 2. When crossed with a strain carrying a gene flanked by loxP sites, the flanked gene will be removed in cells expressing cre. The protein plays a key role in the nervous system.

Mice

Ly6g-2A-CreERT2

Strain Name:C57BL/6Smoc-Ly6gem3(2A-CreERT2)Smoc
Strain State:Repository Live | Cat. NO.:NM-KI-200218

A 2A-CreERT2 expression cassette was knocked into the Ly6g gene stop codon region.

Mice

Hopx-2A-DreERT2

Strain Name:C57BL/6Smoc-Hopxem1(2A-DreERT2)Smoc
Strain State:Repository Live | Cat. NO.:NM-KI-190035

A 2A-DreERT2 expression cassette was knocked into the Hopx gene stop codon site.

Mice

Col2a1-2A-CreERT2

Strain Name:C57BL/6Smoc-Col2a1em1(2A-CreERT2)Smoc
Strain State:Repository Live | Cat. NO.:NM-KI-18029

A 2A-CreERT2 expression cassette was knocked into the stop codon of Col2a1 gene to establish a Col2a1-CreERT2 recombinase tool mouse.The strain cannot breed homozygotes, and it is recommended to use heterozygotes for research.

Mice

Tagln-Cre

Strain Name:C57BL/6Smoc-Taglnem1(Cre-WPRE-polyA)Smoc
Strain State:Repository Live | Cat. NO.:NM-KI-200144

A Cre-WPRE-polyA expression cassette was knocked into the Tagln gene start codon site. This gene encodes a smooth muscle cell-specific cytoskeletal protein. When crossed with a strain carrying a gene flanked by loxP sites, the flanked gene will be removed in vascular smooth muscle cells. In mouse models of atherosclerosis, the gene product may be involved in plaque cell and atherosclerotic lesion formation during atherogenesis.

Mice

Cd2-2A-CreERT2

Strain Name:C57BL/6Smoc-Cd2em1(2A-CreERT2-WPRE-pA)Smoc
Strain State:Repository Live | Cat. NO.:NM-KI-18017

A 2A-CreERT2-WPRE-pA coexpression cassette is inserted befor the stop codon of mouse Cd2 gene via homologous recombination to establish a tamoxifen inducible Cd2-CreERT2 tool stain. This strain can be used to knockout target gene in T cells and B cells after tamoxifen treatment when crossed with mice which carry loxp sites flanking target gene.

Mice

H11-CAG-LSL-mtagBFP2

Strain Name:C57BL/6Smoc-lgs2em1(CAG-LSL-mTagBFP2)Smoc
Strain State:Sperm cryopreservation | Cat. NO.:NM-KI-190006

A CAG-LSL-mTagBFP2-3xFLAG-WPRE-polyA cassette was inserted at the mouse H11 locus. When bred to a strain expressing Cre recombinase under control of various tissue specific promoters, Cre recombination deletes the LSL cassette and allows the expression of the mTagBFP2-3xFLAG protein.

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