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Mice

Cd4-IRES-DTRGFP

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A IRES-DTREGFP expression cassette was knocked into the Cd4 gene stop codon site.

Mice

Trpv1-IRES-Cre

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A Myc-IRES-Cre expression cassette was knocked into the Trpv1 gene stop codon site. Trpv1 is known as transient receptor potential cation channel, subfamily V, member 1. When crossed with a strain carrying a gene flanked by loxP sites, the flanked gene will be removed in cells expressing cre. This strain may be useful for studying the pain caused by heat and capsaicin.

Mice

Foxp3-IRES-DTRGFP

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A IRES-DTREGFP expression cassette was knocked into the Foxp3 gene stop codon site.

Mice

Ncr1-IRES-DTRGFP

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A IRES-DTREGFP expression cassette was knocked into the Ncr1 gene stop codon site.

Mice

Nkx3-1-IRES-Cre

Strain Name：C57BL/6Smoc-Nkx3-1em1(IRES-iCre)Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-KI-200171

A IRES-iCre expression cassette was knocked into the Nkx3-1 gene stop codon site. Nkx3-1 (NK3 homeobox 1) encodes prostate-specific homeodomain protein. The gene product is a key element in protecting prostate epithelial cells from DNA damage. This strain is useful for studying prostate.

Mice

Cd8a-IRES-DTRGFP

Strain Name：C57BL/6Smoc-Cd8aem2(IRES-DTREGFP)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-KI-190045

A IRES-DTREGFP expression cassette was knocked into the Cd8a gene stop codon site.

Mice

Foxp3-IRES-DTR-2A-tdTomato(BALB/c)

Strain Name：BALB/cAnSmoc-Foxp3em9(IRES-DTR-2A-tdTomato)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-KI-200213

A IRES-DTR-2A-tdTomato expression cassette was knocked into the Foxp3 gene stop codon site.

Mice

Ly6g-Cre-2A-tdTomato

Strain Name：C57BL/6Smoc-Ly6gem2(iCre-P2A-tdTomato-polyA)Smoc
Strain State：Repository Live | Cat. NO.：NM-KI-200219

A iCre-P2A-tdTomato-polyA expression cassette was knocked into the Ly6g gene start codon site.

Mice

Rag2-KO(Rag2-EGFP)

Strain Name：B6;129S-Rag2tm1(loxP-EGFP-PolyA-loxP-Neo-loxP)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-KI-00070

A loxP-EGFP-PolyA-loxP-Neo-loxP expression cassette was knocked into the Rag2 gene start codon site. As a Rag2 knockout mouse model, this stain can be used in subcutaneous inoculation of liver cancer tissues and tumor cells. Tumors can esaily form and grow. The amount of T and B lymphocytes in peripheral blood of mice was extremely low tested by FACS, which was comparable to or lower than that of Nude mice, and there was a significant difference compared with wild type mice. The pathological sections of HE staining of tumor tissues showed that the tumor sections of Rag2 KO mice and Nude mice were similar. This strain has the potential to replace Nude, NOD-SCID mice as a tumor-bearing mouse model.

Mice

Shh-EGFP-Cre

Strain Name：C57BL/6Smoc-Shhem1(EGFP-iCre)Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-KI-200232

A EGFP-iCre expression cassette was knocked into the Shh gene start codon site.

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