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Models

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Mice

Lyz2-2A-CreERT2

Strain Name:C57BL/6Smoc-Lyz2em1(2A-CreERT2-WPRE-pA)Smoc
Strain State:Repository Live | Cat. NO.:NM-KI-18018
Validation Data:Presence

A 2A-CreERT2-WPRE-pA coexpression cassette is inserted befor the stop codon of mouse Lyz2 gene via homologous recombination to establish a tamoxifen inducible Lyz2-CreERT2 tool stain. This strain can be used to knockout target gene in Lyz2+ cells after tamoxifen treatment when crossed with mice which carry loxp sites flanking target gene.

Mice

Lyz2-IRES-mtagBFP2-Luc

Strain Name:C57BL/6Smoc-Lyz2em4(IRES-mtagBFP-Luci)Smoc
Strain State:Sperm cryopreservation | Cat. NO.:NM-KI-200029
Validation Data:Presence

A IRES-mtagBFP-luci expression cassette was knocked into the Lyz2 gene stop codon site.

Mice

Esr1-2A-Cre

Strain Name:C57BL/6Smoc-Esr1em1(2A-iCre)Smoc
Strain State:Sperm cryopreservation | Cat. NO.:NM-KI-200164
Validation Data:Presence

A 2A-iCre expression cassette was knocked into the Esr1 gene stop codon site.

Mice

Lyz2-CreERT2-IRES-EGFP

Strain Name:C57BL/6Smoc-Lyz2em2(CreERT2-IRES-EGFP)Smoc
Strain State:Repository Live | Cat. NO.:NM-KI-18047
Validation Data:Presence

A Kozak-CreERT2-IRES-EGFP expression cassette was knocked into the Lyz2 gene start codon site by homologous recombination.

Mice

Mir29a/Mir29b1-KO

Strain Name:C57BL/6Smoc-Mir29aem1 Mir29b-1em1Smoc
Strain State:Sperm cryopreservation | Cat. NO.:NM-KO-00081

a 0.6kb region in length including Mir29a and Mir29b-1 pre-microRNAs was removed in this strain.

Mice

CD8a-IRES-Luc-2A-tdTomato(BALB/c)

Strain Name:BALB/cAnSmoc-CD8aem5(IRES-Akaluc-2A-tdTomato)Smoc
Strain State:Repository Live | Cat. NO.:NM-KI-200208
Validation Data:Presence

A IRES-luci-2A-tdTomato expression cassette was knocked into the CD8a gene stop codon site.

Mice

Fos-2A-Venus-Luc

Strain Name:C57BL/6Smoc-Fosem3(2A-Venus-Akaluci)Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-KI-190049

A 2A-Venus-luci expression cassette was knocked into the Fos gene stop codon site.

Mice

Hcn4-DreERT2

Strain Name:C57BL/6Smoc-Hcn4em1(kozak-DreER-WPRE-A)Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-KI-200199
Publications:1piece

A kozak-DreER-WPRE-pA expression cassette was knocked into the Hcn4 gene start codon site.

Mice

Cdkn2a-Luc-2A-tdTomato-2A-CreERT2(p16-Luc-2A-tdTomato-2A-CreERT2)

Strain Name:C57BL/6Smoc-Cdkn2aem(Luc-tdTomato-CreERT2)Smoc
Strain State:Repository Live | Cat. NO.:NM-KI-18039
Validation Data:Presence  |  Publications:1piece

A Luc-2A-tdTomato-2A-CreERT2-WPRE-pA cassette was fused in-frame with exon2 of p16INK4a transcript such that the exogenous proteins would be translated followed by the first 62aa of Cdkn2a.

Mice

Zbtb46-IRES-Cre

Strain Name:C57BL/6Smoc-Zbtb46em1(IRES-iCre)Smoc
Strain State:Repository Live | Cat. NO.:NM-KI-200096
Validation Data:Presence

A IRES-iCre expression cassette was knocked into the Zbtb46 gene stop codon site.

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