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Mice

Acta2-CreERT2

Strain Name:C57BL/6JSmo-Acta2em1(CreERT2-Wpre-polyA)Smoc
Strain State:Repository Live | Cat. NO.:NM-KI-200074
Validation Data:Presence

A CreERT2-Wpre-polyA expression cassette was knocked into the Acta2 gene start codon site.

Mice

Adgre1-2A-CreERT2

Strain Name:C57BL/6JSmo-Adgre1em1(2A-CreERT2)Smoc
Strain State:Repository Live | Cat. NO.:NM-KI-190025
Validation Data:Presence

A 2A-CreERT2 expression cassette was knocked into the Adgre1 gene stop codon site.

Mice

Ace2-2A-CreERT2

Strain Name:C57BL/6JSmo-Ace2em2(2A-CreERT2-WPRE-polyA)Smoc
Strain State:Sperm cryopreservation | Cat. NO.:NM-KI-200187
Validation Data:Presence

A 2A-CreERT2-WPRE-polyA expression cassette was knocked into the Ace2 gene stop codon site. Ace2 encodes angiotensin I converting enzyme 2. When crossed with a strain carrying a gene flanked by loxP sites, the flanked gene will be removed in cells expressing Cre. This strain is useful for studying lung injury and kidney disease caused by SARS coronavirus infection.

Mice

Acadm-repeat(E8-10)

Strain Name:C57BL/6JSmo-Acadmem1(E8-10 repeat)Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-KI-200239

A E8-10 repeat cassette was knocked after exon10 of the Acadm gene.

Mice

a-IRES-Cre

Strain Name:C57BL/6JSmo-atm1(Cre)Smoc
Strain State:Sperm cryopreservation | Cat. NO.:NM-KI-200027
Publications:1piece

A IRES-Cre expression cassette was knocked into the a gene stop codon site via ESC targeting. Male mice with a germline Cre leak expression condition, please use female mice and flox mice for breeding crosses. References are available, please see the website for details.

Mice

Aicda-Cre

Strain Name:C57BL/6JSmo-Aicdaem1(Cre-WPRE-polyA)Smoc
Strain State:Sperm cryopreservation | Cat. NO.:NM-KI-200160
Validation Data:Presence

A Cre-WPRE-polyA expression cassette was knocked into the Aicda gene start codon site.

Mice

Aplnr-2A-DreERT2

Strain Name:C57BL/6JSmo-Aplnrem1(2A-DreERT2)Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-KI-00132
Publications:1piece

A 2A-DreERT2-SV40polyA coexpression cassette is inserted befor the stop codon of mouse Aplnr gene via homologous recombination to establish a tamoxifen inducible Aplnr-DreERT2 tool stain. This strain can be used to knockout target gene in Aplnr+ cells after tamoxifen treatment when crossed with mice which carry rox sites flanking target gene.

Mice

Aqp5-Cre

Strain Name:C57BL/6JSmo-Aqp5em1(iCre-WPRE-polyA)Smoc
Strain State:Sperm cryopreservation | Cat. NO.:NM-KI-200062
Validation Data:Presence

A iCre-WPRE-polyA expression cassette was knocked into the Aqp5 gene start codon site.

Mice

Axin2-CreERT2

Strain Name:C57BL/6JSmo-Axin2em1(CreERT2-pA)Smoc
Strain State:Sperm cryopreservation | Cat. NO.:NM-KI-200109
Validation Data:Presence

A CreERT2-pA expression cassette was knocked into the Axin2 gene start codon site. As Axin2 is an intracellular protein, it is essential for identifying a surface marker for stem cell purification. When these Axin2-CreERT2 mice are bred with mice containing a loxP-flanked sequence of interest, tamoxifen-inducible, Cre-mediated recombination will result in deletion of the flanked sequences in Axin2 expressing cells.

Mice

Alb-DreERT2

Strain Name:C57BL/6JSmo-Albem1(Kozak-DreERT2-WPRE-pA)Smoc
Strain State:Sperm cryopreservation | Cat. NO.:NM-KI-200076

A Kozak-DreERT2-WPRE-pA expression cassette was knocked into the Alb gene start codon site.

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