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Models

About 64 results
Mice

Flt4-KO

Strain Name:C57BL/6Smoc-Flt4em1Smoc
Strain State:Sperm cryopreservation | Cat. NO.:NM-KO-225086

Exon 2 of Flt4 gene was deleted to generate Flt4 knockout mice.

Mice

hTL1A(3)

Strain Name:C57BL/6Smoc-Tnfsf15tm2(hTNFSF15)Smoc
Strain State:Repository Live | Cat. NO.:NM-HU-233157
Validation Data:Presence

The endogenous mouse Tnfsf15 gene was replaced by human TNFSF15 gene.

Mice

Prokr2-Flox

Strain Name:C57BL/6Smoc-Prokr2em1(flox)Smoc
Strain State:Sperm cryopreservation | Cat. NO.:NM-CKO-232275

These strains carry loxP sites flanking exon 2 of Prokr2 gene. When crossed with a Cre recombinase-expressing strain, this strain is useful in eliminating tissue-specific conditional expression of Prokr2 gene.

Mice

Prokr2-KO

Strain Name:C57BL/6Smoc-Prokr2em1Smoc
Strain State:Sperm cryopreservation | Cat. NO.:NM-KO-225039

exon 3 of Prokr2 gene was deleted to generate Prokr2 knockout mice.

Mice

Prokr1-KO

Strain Name:C57BL/6Smoc-Prokr1em1Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-KO-200433

Exon 3 of Prokr1 gene was deleted to generate Prokr1 knockout mice.

Mice

Prokr1-Flox

Strain Name:C57BL/6Smoc-Prokr1em1(flox)Smoc
Strain State:Developing | Cat. NO.:TBD

These mice carry loxP sites flanking target exons of Prokr1 gene. When crossed with a Cre recombinase-expressing strain, this strain is useful in eliminating tissue-specific conditional expression of Prokr1 gene.

Mice

Kdr-KO

Strain Name:C57BL/6Smoc-KdremSmoc
Strain State:Sperm cryopreservation | Cat. NO.:NM-KO-210385

exon 1 of Kdr gene was deleted to generate Kdr knockout mice.

Rats

Kdr-KO(SD)

Strain Name:SD-Kdrem1Smoc Strain State:Repository Live | Cat. NO.:NR-KO-232073

The exon 1-30 of Kdr gene was deleted to generate Kdr knockout rat.

Literature

HIF-1alpha and HIF-2alpha induced angiogenesis in gastrointestinal vascular malformation and reversed by thalidomide

Model Organisms:斑马鱼 Product & Service:HIF-2alpha Research field:Drug screening and drug mechanism

血管生成 Thalidomide 血管内皮生长因子 VEGF

Literature

Endothelial CDS2 Deficiency Causes VEGFA-mediated Vascular Regression and Tumor Inhibition

Model Organisms:Mouse Product & Service:cds2 Research field:Vascular Regression

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