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Models

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Mice

Plp1-Flox

Strain Name：C57BL/6Smoc-Plp1em1(flox)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-CKO-200072

These mice carry loxP sites flanking exon 3 of Plp1 gene. When crossed with a Cre recombinase-expressing strain, this strain is useful in eliminating tissue-specific conditional expression of Plp1 gene.

Mice

CAG-hACE2-IRES-Luc-Tg

Strain Name：C57BL/6Smoc-Tgtn(CAG-human ACE2-IRES-Luciferase-WPRE-polyA)Smoc
Strain State：Repository Live | Cat. NO.：NM-TG-200002
Validation Data：Presence  |  Publications：2piece

The transgene is composed of a CAG-human ACE2-IRES-Luciferase-WPRE-polyA expression cassette under the control of CAG promter.

Mice

hPD-L1

Strain Name：C57BL/6Smoc-Cd274tm1(hPD-L1)Smoc
Strain State：Repository Live | Cat. NO.：NM-HU-00062
Validation Data：Presence  |  Publications：1piece

The endogenous mouse Cd274(also known as PD-L1) gene was replaced by human PD-L1 gene . While hPD-L1(2)(Stock No.NM-HU-190039) mice function similarly to hPD-L1 mice,for more detailed information please contact our technical advisor.

Mice

hCD81

Strain Name：C57BL/6Smoc-Cd81tm1(CD81)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-190041

The endogenous mouse Cd81 gene was replaced by human CD81 gene.

Mice

hDPP4

Strain Name：C57BL/6Smoc-Dpp4tm1(DPP4)Smoc
Strain State：Repository Live | Cat. NO.：NM-HU-190042
Validation Data：Presence  |  Publications：1piece

The endogenous mouse Dpp4 gene was replaced by human DPP4 gene.

Mice

h4-1BB(2)

Strain Name：C57BL/6Smoc-Tnfrsf9tm2(TNFRSF9)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-190077
Validation Data：Presence

The endogenous mouse Tnfrsf9 gene was replaced by human TNFRSF9(4-1BB) gene. While h4-1BB mice(Stock No.NM-HU-00099）have been pulled from shelves for some reasons.

Mice

h4-1BBL

Strain Name：C57BL/6Smoc-Tnfsf9tm1(hTNFSF9)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-00048
Validation Data：Presence

The endogenous mouse Tnfsf9 gene was replaced by human TNFSF9 gene.

Mice

hANGPTL3(4)

Strain Name：C57BL/6Smoc-Angptl3tm1(hANGPTL3)Smoc
Strain State：Repository Live | Cat. NO.：NM-HU-210036
Validation Data：Presence

The endogenous mice Angptl3 gene was replaced by human ANGPTL3 gene. While hANGPTL3(Stock No.NM-HU-200113) have been pulled from shelves for some reasons and hANGPTL3(3)(Stock No.NM-HU-210037) mice function similarly to hANGPTL3(2) mice, for more detailed information please contact our technical advisor.

Mice

Rag2/IL2rg-KO/hCD40

Strain Name：C57BL/6Smoc-Cd40tm1(hCD40)Rag2em1Il2rgem1Smoc
Strain State：Developing | Cat. NO.：NM-HU-2000112

The Rag2 and Il2rg genes of the CD40 humanized mouse were deleted.

Mice

hOCLN

Strain Name：C57BL/6Smoc-Oclntm1(hOCLN)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-190072

The endogenous mouse Ocln gene was replaced by human OCLN gene.

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