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Models

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Mice

Sidt2-Flox

Strain Name:B6;129S-Sidt2tm1(flox)Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-CKO-00041

The Sidt2 flox allele has loxP sites flanking exon 2 of Sidt2 gene. When crossed with a Cre recombinase-expressing strain, this strain is useful in eliminating tissue-specific conditional expression of the gene.

Mice

Npr3-2A-DreERT2

Strain Name:C57BL/6Smoc-Npr3em1(2A-DreERT2)Smoc
Strain State:Sperm cryopreservation | Cat. NO.:NM-KI-190015
Validation Data:Presence  |  Publications:1piece

The 2A-DreERT2 cassette is inserted before 3'UTR region of Npr3 gene.

Mice

hIL3

Strain Name:C57BL/6Smoc-Il3tm1(hIL3)Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-HU-190009

The endogenous mouse Il3 gene was replaced by human IL3 gene.

Mice

hLY96

Strain Name:C57BL/6Smoc-Ly96tm1(hLY96)/Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-HU-210003
Validation Data:Presence

The endogenous mice Ly96 gene was replaced by human LY96 gene

Mice

Cd8a-2A-CreERT2

Strain Name:C57BL/6Smoc-Cd8aem1(2A-CreERT2)Smoc
Strain State:Sperm cryopreservation | Cat. NO.:NM-KI-234690
Validation Data:Presence

The 2A-CreERT2 expression cassette was knocked into the Cd8a gene stop codon site.

Mice

hIL3/hCSF2

Strain Name:C57BL/6Smoc-Il3tm3(hIL3)Csf2tm3(hCSF2)/Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-HU-190065
Validation Data:Presence

The endogenous mouse Il3 and Csf2 gene was replaced by human IL3 and CSF2 gene.

Mice

hIL4

Strain Name:C57BL/6Smoc-Il4tm3(hIL4)Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-HU-190071
Validation Data:Presence

The endogenous mouse Il4 gene was completely or partially replaced by human IL4 gene via ESC targeting.

Mice

Fcgr2b-Fcgr3-Fcgr4-KO/hPD-1/hCTLA-4

Strain Name:C57BL/6Smoc-Fcgr2bem1Fcgr3em1Fcgr4em1Pdcd1em1(hPDCD1)Ctla4em1(hCTLA4)Smoc
Strain State:Sperm cryopreservation | Cat. NO.:NM-KO-220070

The Fcgr2b-Fcgr3-Fcgr4-KO/hPD-1/hCTLA4 mouse model was obtained by deleting sequences from upstream of Fcgr3 gene to the 3'UTR of Fcgr2b gene in the hPD-1/hCTLA4(NM-HU-00079) mouse.

Mice

hADAM17

Strain Name:C57BL/6Smoc-Adam17tm(hADAM17)Smoc
Strain State:Developing | Cat. NO.:NM-HU-220260

The endogenous mouse Adam17 gene was replaced by human ADAM17 gene.

Mice

Sidt2-KO

Strain Name:C57BL/6Smoc-Sidt2em1Smoc
Strain State:Sperm cryopreservation | Cat. NO.:NM-KO-253522

The exon 7-8 of Sidt2 gene was deleted to generate Sidt2 knockout mouse.

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