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Models

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Mice

hPVRIG

Strain Name:C57BL/6Smoc-Pvrigtm1(hPVRIG)/Smoc
Strain State:Repository Live | Cat. NO.:NM-HU-210008
Validation Data:Presence

The endogenous mice Pvrig gene was replaced by human PVRIG gene While hPVRIG(2)(Stock No.NM-HU-215013) mice function similarly to hPVRIG mice, for more detailed information please contact our technical advisor.

Mice

hIL2RB

Strain Name:C57BL/6Smoc-Il2rbtm1(hIL2RB)/Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-HU-2000055
Validation Data:Presence

The endogenous mouse Il2rb gene was replaced by human IL2RB gene.

Mice

hCD74

Strain Name:C57BL/6Smoc-Cd74tm1(hCD74)/Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-HU-2000082

The endogenous mouse Cd74 gene was replaced by human CD74 gene.

Mice

hSLAMF7

Strain Name:C57BL/6Smoc-Slamf7tm(hSLAMF7)Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-HU-18028

The endogenous mouse Slamf7 gene was replaced by human SLAMF7 gene .

Mice

hSORT1

Strain Name:C57BL/6Smoc-Sort1tm1(hSORT1)Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-HU-225035
Validation Data:Presence

The endogenous mouse Sort1 gene was replaced by human SORT1 gene.

Mice

Bhlha15-CreERT2

Strain Name:C57BL/6Smoc-Bhlha15em1(CreERT2)Smoc
Strain State:Sperm cryopreservation | Cat. NO.:NM-KI-200080
Validation Data:Presence

The coding region of Bhlha15 gene was replaced by a CreERT2 expression cassette.Besides,a kozak-CreERT2-WPRE-polyA expression cassette were knock into the Bhlha15 gene start codon site to generate Bhlha15-CreERT2(2)(Stock No. NM-KI-200158) mice. Bhlha15(basic helix-loop-helix family member a15) is also known as Mist1. The gene product is involved in controlling exocrine secretion from the pancreas, small intestine and stomach. When crossed with a strain carrying a gene flanked by loxP sites, the flanked gene will be removed in cells expressing Bhlha15.

Mice

hSIGLEC15

Strain Name:C57BL/6Smoc-Siglec15tm1(hSIGLEC15)Smoc
Strain State:Repository Live | Cat. NO.:NM-HU-190037
Validation Data:Presence

The endogenous mouse Siglec15 gene was replaced by human SIGLEC15 gene.

Mice

hTROP2

Strain Name:C57BL/6Smoc-Tacstd2tm(hTACSTD2)Smoc
Strain State:Repository Live | Cat. NO.:NM-HU-215022
Validation Data:Presence

The endogenous mice Tacstd2 gene was replaced by human TACSTD2 gene.

Mice

hICOSL

Strain Name:C57BL/6Smoc-Icosltm1(hICOSLG) Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-HU-00095
Validation Data:Presence

The endogenous mouse Icosl gene was replaced by human ICOSL gene . While hICOSL(2)(Stock No.NM-HU-2000068) mice function similarly to hICOSL mice,for more detailed information please contact our technical advisor.

Mice

hIL7R

Strain Name:C57BL/6Smoc-Il7rtm1(hIL7R)Smoc
Strain State:Repository Live | Cat. NO.:NM-HU-210027
Validation Data:Presence

The endogenous mice Il7r gene was completely or partially replaced by human IL7R gene via ESC targeting.

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