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Models

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Mice

hCD24

Strain Name：C57BL/6Smoc-Cd24atm1(hCD24)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-2000060
Validation Data：Presence

The endogenous mouse Cd24a gene was replaced by human CD24 gene. While hCD24(2)(Stock No.NM-HU-215025) mice function similarly to hCD24 mice, for more detailed information please contact our technical advisor.

Mice

hCCR8(BALB/c)

Strain Name：BALB/cAnSmoc-Ccr8tm1(hCCR8)/Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-2000048
Validation Data：Presence

The endogenous mouse Ccr8 gene was replaced by human CCR8 gene.

Mice

hTTR

Strain Name：C57BL/6Smoc-Ttrtm1(hTTR)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-225087
Validation Data：Presence

The endogenous mouse Ttr gene was replaced by human TTR gene.

Mice

hALB

Strain Name：C57BL/6Smoc-Albtm3(ALB)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-200003
Validation Data：Presence

The endogenous mouse Alb gene was replaced by human ALB gene.

Mice

hTLR8

Strain Name：C57BL/6Smoc-Tlr8tm2(TLR8)Smoc
Strain State：Repository Live | Cat. NO.：NM-HU-190044
Validation Data：Presence

The endogenous mouse Tlr8 gene was replaced by human TLR8 gene.

Mice

hCD3E

Strain Name：C57BL/6Smoc-Cd3etm1(hCD3E) Smoc
Strain State：Repository Live | Cat. NO.：NM-HU-00114
Validation Data：Presence

The endogenous mouse Cd3e gene was replaced by human CD3E gene . While hCD3E(2)(Stock No.NM-HU-210023) mice function similarly to hCD3E mice,for more detailed information please contact our technical advisor.

Mice

hCRBN

Strain Name：C57BL/6Smoc-Crbntm1(hCRBN)Smoc
Strain State：Repository Live | Cat. NO.：NM-HU-225071
Validation Data：Presence

The endogenous mouse Crbn gene was replaced by human CRBN gene.

Mice

HLA-A2.22/B2M

Strain Name：C57BL/6Smoc-H2-D1tm1(hB2M/HLA-A2)/Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-HU-210010

The endogenous mice H2-D1 gene was replaced by human B2M/HLA-A2 gene

Mice

hCD27(2)

Strain Name：C57BL/6Smoc-Cd27tm3(hCD27)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-190035
Validation Data：Presence

The endogenous mouse Cd27 gene was replaced by human CD27 gene. While hCD27 mice(Stock No.NM-HU-00093）have been pulled from shelves for some reasons.

Mice

NOD SCID

Strain Name：NOD.Cg-Prkdcscid/NifdcSmoc
Strain State：Repository Live | Cat. NO.：SM-019
Validation Data：Presence

The strain was developed on background of non-obese diabetic (NOD) mouse with spontaneous scid mutation. NOD SCID mouse, insusceptible to diabetes, possesses reduced activity of T cells and B cells, and defect in innate immunity.NOD SCID mouse is compatible with a wider range of engraftment of cell lines in comparison with nude mouse; And it is broadly applied to construction of PDX models. However, due to a short life span(8-9 months) caused by lethal thymic lymphomas, it is unsuitable for long-term in vivo assays.

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