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Models

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Mice

hCD40

Strain Name：C57BL/6Smoc-Cd40tm1(hCD40) Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-00076
Validation Data：Presence

The endogenous extracellular mouse Cd40 gene was replaced by the extracellular region of human CD40 gene.

Mice

hCD28

Strain Name：C57BL/6Smoc-Cd28tm2(hCD28)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-190011
Validation Data：Presence

The endogenous mouse Cd28 gene was replaced by human CD28 gene.

Mice

hC5

Strain Name：C57BL/6Smoc-Hctm1(hC5)Smoc
Strain State：Repository Live | Cat. NO.：NM-HU-2000013
Validation Data：Presence

The endogenous mouse C5a gene was replaced by human C5 gene.

Mice

hHBB

Strain Name：C57BL/6Smoc-Hbb-bt&Hbb-bstm1(hHBB)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-2000080
Validation Data：Presence

The endogenous mouse Hbb-bt and Hbb-bs gene was replaced by human HBB gene.

Mice

hCCR1

Strain Name：C57BL/6Smoc-Ccr1tm3(hCCR1)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-190067

The endogenous mouse Ccr1 gene was replaced by human CCR1 gene.

Mice

hHGF(NOD-scid)

Strain Name：NOD-PrkdcscidHgftm1(hHGF)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-190062
Validation Data：Presence

The endogenous mouse Hgf gene was replaced by human HGF gene.

Mice

hAppNL-G-F

Strain Name：C57BL/6Smoc-Apptm3(hAppNL-G-F)/Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-2000088
Validation Data：Presence

The endogenous mouse App gene was replaced by human AppNL-G-F.

Mice

hC5AR1/C5AR2

Strain Name：C57BL/6Smoc-C5ar1tm1(hC5AR1)C5ar2tm1(hC5AR2)/Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-2000018
Validation Data：Presence

The endogenous mouse C5ar1 and C5ar2 gene was replaced by human C5AR1 and hC5AR2 gene.

Mice

hGLP1R

Strain Name：C57BL/6Smoc-Glp1rtm2(hGLP1R)Smoc
Strain State：Repository Live | Cat. NO.：NM-HU-200220
Validation Data：Presence  |  Publications：1piece

The endogenous mouse Glp1r gene was completely or partially replaced by human hGLP1R gene via CRISPR/Cas9 mediated recombination.

Mice

hCTLA-4

Strain Name：C57BL/6Smoc-Ctla4tm1(hCTLA4) Smoc
Strain State：Repository Live | Cat. NO.：NM-HU-00014
Validation Data：Presence

The endogenous mouse Ctal4 gene was replaced by human CTLA4 gene. While hCTLA4(2)(Stock No.NM-HU-190038) mice function similarly to hCTLA4 mice,for more detailed information please contact our technical advisor.

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