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Models

About 118 results
Mice

Trem2-KO

Strain Name：C57BL/6Smoc-Trem2em1Smoc
Strain State：Repository Live | Cat. NO.：NM-KO-190402

This Trem2 knockout mouse model was generated by knocking out the exon2-3 region of the Trem2.

Mice

Trem2-Flox

Strain Name：C57BL/6Smoc-Trem2tm2(flox)Smoc
Strain State：Repository Live | Cat. NO.：NM-CKO-190063

These mice carry loxP sites flanking exon 2-3 of Trem2 gene. When crossed with a Cre recombinase-expressing strain, this strain is useful in eliminating tissue-specific conditional expression of Trem2 gene.

Mice

Trem2-R62H

Strain Name：C57BL/6Smoc-Trem2em1(R62H)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-KI-210225

These mice carry a R62H mutation of Trem2 gene.

Mice

Trem2-R47H

Strain Name：C57BL/6Smoc-Trem2em3(p.R47H)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-KI-190092

These mice carry a p.R47H mutation of Trem2 gene.

Mice

Trem1-KO

Strain Name：C57BL/6Smoc-Trem1em1Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-KO-200552

Exon 2-3 of Trem1 gene was deleted to generate Trem1 knockout mice.

Mice

Trex1-KO

Strain Name：C57BL/6Smoc-Trex1em1Smoc
Strain State：Repository Live | Cat. NO.：NM-KO-232136

The exon 2 of Trex1 gene was deleted to generate Trex1 knockout mouse.

Mice

Treml1-KO(2)

Strain Name：C57BL/6Smoc-Treml1em3Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-KO-251256

The exon 1-2 of Treml1 gene was deleted to generate Treml1 knockout mouse.

Mice

Trem3-KO

Strain Name：C57BL/6Smoc-Trem3em1Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-KO-201964

Exon 2-3 of Trem3 gene was deleted to generate Trem3 knockout mice.

Mice

Col1a1-TRE3G-dCas9-VPR-EGFP

Strain Name：C57BL/6Smoc-Col1a1em1(TRE3G-dCas9-VPR-eGFP-pA)Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-KI-00123

These mice harbor a TRE3G-dCas9-VPR(VP64-p65-Rta)-eGFP-pA tetracycline-controlled transcriptional activation cassette in mouse Col1a1 loci. This strain can be used in CRISPR mediated target gene transcriptional activation (CRISPRa).

Mice

R26-CAG-LSL-Trem2

Strain Name：C57BL/6Smoc-Gt(ROSA)26Sorem(CAG-Loxp-Stop-Loxp-Trem2-Wpre-pA)Smoc
Strain State：Repository Live | Cat. NO.：NM-KI-215105

CAG-Loxp-Stop-Loxp-Trem2-Wpre-pA expression cassette was knocked into the the Rosa26 locus.

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