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Models

About 116 results
Mice

Treh-KO

Strain Name：C57BL/6Smoc-Trehem1Smoc
Strain State：Developing | Cat. NO.：TBD

Exon 2 of Treh gene was deleted to generate Treh knockout mice.

Mice

Trex2-Flox

Strain Name：C57BL/6Smoc-Trex2em1(flox)Smoc
Strain State：Developing | Cat. NO.：TBD

These mice carry loxP sites flanking target exons of Trex2 gene. When crossed with a Cre recombinase-expressing strain, this strain is useful in eliminating tissue-specific conditional expression of Trex2 gene.

Mice

Trex2-KO

Strain Name：C57BL/6Smoc-Trex2em1Smoc
Strain State：Developing | Cat. NO.：TBD

Exon 2 of Trex2 gene was deleted to generate Trex2 knockout mice.

Mice

Trem1-KO(2)

Strain Name：C57BL/6Smoc-Trem1em1Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-KO-235031

The exon 2 of Trem1 gene was deleted to generate Trem1 knockout mouse.

Mice

Trem3-KO(2)

Strain Name：C57BL/6Smoc-Trem3em2Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-KO-233011

The exon 2 of Trem3 gene was deleted to generate Trem3 knockout mouse.

Mice

Trem2-Y38C

Strain Name：C57BL/6Smoc-Trem2em1Y38CSmoc
Strain State：Developing | Cat. NO.：NM-KI-242955

These strains carry a Y38C mutation of Trem2 gene.

Mice

Trex1-Flox

Strain Name：C57BL/6Smoc-Trex1em1(flox)Smoc
Strain State：Developing | Cat. NO.：NM-CKO-242460

These strains carry loxP sites flanking exon 2 of Trex1 gene. When crossed with a Cre recombinase-expressing strain, this strain is useful in eliminating tissue-specific conditional expression of Trex1 gene.

Mice

Col1a1-TRE3G-dCas9-VPR-EGFP

Strain Name：C57BL/6Smoc-Col1a1em1(TRE3G-dCas9-VPR-eGFP-pA)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-KI-00123

These mice harbor a TRE3G-dCas9-VPR(VP64-p65-Rta)-eGFP-pA tetracycline-controlled transcriptional activation cassette in mouse Col1a1 loci. This strain can be used in CRISPR mediated target gene transcriptional activation (CRISPRa).

Mice

R26-CAG-LSL-Trem2

Strain Name：C57BL/6Smoc-Gt(ROSA)26Sorem(CAG-Loxp-Stop-Loxp-Trem2-Wpre-pA)Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-KI-215105

CAG-Loxp-Stop-Loxp-Trem2-Wpre-pA expression cassette was knocked into the the Rosa26 locus.

Mice

hTREM2

Strain Name：C57BL/6Smoc-Trem2em4(hTRem2)/Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-2000083

The endogenous mouse Trem2 gene was replaced by human TREM2 gene.

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