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Models

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Mice

hCD40/h4-1BB(2)

Strain Name:C57BL/6Smoc-Cd40em1(hCD40)Tnfrsf9tm2(TNFRSF9)Smoc
Strain State:Repository Live | Cat. NO.:NM-HU-200256

hCD40(NM-HU-00076)was crossed with h4-1BB(NM-HU-190077)to generate hCD40/h4-1BB(2) mice.

Mice

hCD40/hCD40L

Strain Name:C57BL/6Smoc-CD40em2(hCD40)Cd40lgtm1(hCD40L)/Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-HU-200268

hCD40(NM-HU-00076)was crossed with hCD40L(NM-HU-2000033)to generate hCD40/hCD40L mice

Mice

hPD-1/hCD40

Strain Name:C57BL/6Smoc-Pdcd1em1(hPDCD1)Cd40em1(hCD40)Smoc
Strain State:Repository Live | Cat. NO.:NM-HU-190017

hPD-1(NM-HU-00015) was crossed with hCD40(NM-HU-00076) to generate hPD-1/hCD40.

Mice

Tap1-KO

Strain Name:C57BL/6Smoc-Tap1em1Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-KO-190194

Tap1-KO mice(Stock No.NM-KO-190194)carry a knockout allele derived from the targeted deletion of exon 1-12. While Tap1-KO(2) mice (Stock No.NM-KO-201935) carrying the exon 2 deletion.

Mice

Tap2-KO

Strain Name:C57BL/6Smoc-Tap2em1Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-KO-190884

Exon 4 of Tap2 gene was deleted to generate Tap2 knockout mice.

Mice

hPD-L1/hCD40

Strain Name:C57BL/6Smoc-Cd274em1(hPD-L1)Cd40em1(hCD40)Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-HU-18024

hPD-L1(NM-HU-00062) was crossed with hCD40(NM-HU-00076) to generate hPD-L1/hCD40.

Mice

hCD40/hPD-1/hPD-L1

Strain Name:C57BL/6Smoc-Cd40em1(hCD40)Pdcd1em1(hPDCD1)Cd274em1(hPD-L1)/Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-HU-210406

hPD-1/hPD-L1(NM-HU-00100) was crossed with hCD40(NM-HU-00076)to generate hCD40/hPD-1/hPD-L1 mice

Mice

hFCGR2B/hCD40

Strain Name:C57BL/6Smoc-Fcgr2Bem1(hFCGR2B)Cd40em1(hCD40)/Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-HU-200262

hFCGR2B(NM-HU-2000010) was crossed with hCD40(NM-HU-00076)to generate hFCGR2B/hCD40 mice.

Literature
Pages

Osteoporosis

osteoporosis gene osteoporosis diseases Tnfrsf11b

Tnfrsf11b (Opg) knockout mice were generated through homologous recombination and supplied by Shanghai Research Center for Model Organisms. This mouse model, which is referred to as the "osteoporotic mouse", shows a typical phenotype of osteoporosis and arterial calcification, and Therefore, this animal model is ideal for drug screening and evaluation for the treatment of "human osteoporosis", in gene therapy of osteoporosis, as well as in the research on the mechanisms of interaction between osteoclasts and osteoblasts.

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