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Models

About 115 results
Mice

Hnf4a-Flox

Strain Name：C57BL/6Smoc-Hnf4atm1(flox)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-CKO-190062

These Hnf4a flox mice possess loxP sites flanking exon 2. When crossed with a Cre recombinase-expressing strain, this strain is useful in eliminating tissue-specific conditional expression of the gene.

Mice

Lrp5-KO

Strain Name：C57BL/6Smoc-Lrp5em1Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-KO-190683

Exon 2 of Lrp5 gene was deleted to generate Lrp5 knockout mice.

Mice

Fzd4-KO

Strain Name：C57BL/6Smoc-Fzd4em1Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-KO-190678

Exon 1-2 of Fzd4 gene was deleted to generate Fzd4 knockout mice.

Mice

Myb-KO

Strain Name：C57BL/6Smoc-Mybem1Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-KO-190617

Exon 2 of Myb gene was deleted to generate Myb knockout mice.

Mice

Nkx3-1-IRES-CreERT2

Strain Name：C57BL/6Smoc-Nkx3-1em1(IRES-CreERT2)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-KI-200071

A IRES-CreERT2 expression cassette was knocked into the Nkx3-1 gene stop codon site.

Mice

Cdkn2b-KO(p15-KO)

Strain Name：C57BL/6Smoc-Cdkn2Bem1Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-KO-190621

Exon 2 of Cdkn2b gene was deleted to generate Cdkn2b knockout mice.

Mice

Rp1-KO

Strain Name：C57BL/6Smoc-Rp1em1Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-KO-190142

This Rp1 knockout mouse model was generated by knocking out the exon 4 region of the Rp1.

Mice

Coll1a1-pTRE-Msi1/Krt14-rtTA

Strain Name：Coll1a1-pTRE-Msi1/Krt14-rtTA
Strain State：Embryo cryopreservation | Cat. NO.：NM-KI-210411

Expression of the Msi1 gene can be regulated by the tetracycline analog, doxycycline (dox); in the presence of dox, transcription of the Msi1 gene is induced in cells where rtTA is expressed.

Mice

Il1b-Luc-Tg

Strain Name：B6.Cg-Tg(IL1B-luc)Smoc
Strain State：Repository Live | Cat. NO.：NM-TG-00001

The transgenic mice model could be used to study transcriptional regulation of the IL-1βgene expression in the inflammatory process and evaluation the effect of anti-inflammatory drug in vivo.

Mice

Foxp3-IRES-tdTomato-2A-Cre

Strain Name：C57BL/6Smoc-Foxp3em3(IRES-tdTomato-2A-iCre)Smoc
Strain State：Repository Live | Cat. NO.：NM-KI-190119

A IRES-tdTomato-2A-Cre expression cassette was knocked into the Foxp3 gene stop codon site. This strain is useful in studying regulatory T cell in autoimmunity, especially in type 1 diabetes.

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