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Models

About 161 results
Mice

Pah-KO

Strain Name：C57BL/6Smoc-Pahem1Smoc
Strain State：Repository Live | Cat. NO.：NM-KO-2110565
Validation Data：Presence

Exon 2-5 of pah gene was deleted to generate pah knockout mice. The homozygous (HO) mice have a certain mortality rate (approximately 15%). Heterozygous (HE) mice are recommended for colony establishment. If you need to purchase homozygous (HO) mice directly for experiments, it is recommended to purchase an additional 15%-20% to avoid mouse death affecting subsequent experiments.

Mice

H11-pThy1-hPSEN1-IRES-tdTomato

Strain Name：C57BL/6Smoc-Igs2tm1(pThy1-PSEN1-IRES-tdTomato-WPRE-pA)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-KI-18049

A Thy1 promoter-PSEN1-IRES-tdTomato-WPRE-polyA cassette was knocked into the Igs2 locus (Hipp11 or H11; an intergenic region on chromosome 11 [cytoband A1 at ~3cM between the Eif4enif1 and Drg1 loci] reported to support high-level global gene expression in conjunction with the CAG (CAGGS) promoter and a higher rate of mitotic/interchromosomal recombination compared to Gt(ROSA)26Sor) .

Mice

H11-CAG-RSR-EYFP

Strain Name：C57BL/6Smoc-Igs2em1(CAG-RSR-EYFP)Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-KI-18056

A CAG-ROX-STOP-ROX-EYFP-V5tag-polyA conditional expression cassette was knocked into the Igs2 locus (Hipp11 or H11; an intergenic region on chromosome 11 [cytoband A1 at ~3cM between the Eif4enif1 and Drg1 loci] reported to support high-level global gene expression in conjunction with the CAG (CAGGS) promoter and a higher rate of mitotic/interchromosomal recombination compared to Gt(ROSA)26Sor) . This strain of mice can be used to mate with mice expressing the Dre recombinase. After exposure to Dre recombinase, expression of ellow fluorescent protein and V5 tag is observed for cell tracking.

Mice

Brs3-KO

Strain Name：C57BL/6Smoc-Brs3em1Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-KO-190608

Exon 2 of Brs3 gene was deleted to generate Brs3 knockout mice.

Rats

hGIPR(SD)

Strain Name：SD-Giprem1(hGIPR)Smoc Strain State：Repository Live | Cat. NO.：NR-HU-225067
Validation Data：Presence

The endogenous rat Gipr gene was replaced by human GIPR gene.

Rats

Tigre-TetO-Cre-IRES-EGFP(SD)

Strain Name：SD-lgs7em1(tetO-Cre-IRES-EGFP)Smoc Strain State：Embryo cryopreservation | Cat. NO.：NR-KI-200005

These rat harbor a tetO-Cre-IRES-EGFP cassette in the TIGRE locus generated by homologous recombination.

Rats

R26-CAG-LSL-Cas9-IRES-tdTomato(SD)

Strain Name：SD-Gt(ROSA)26Sorem1(CAG-LSL-Cas9-FRT-IRES-tdTomato-FRT-WPRE-polyA)Smoc Strain State：Repository Live | Cat. NO.：NR-KI-200004

These rats harbor a CAG-LSL-Cas9-FRT-IRES-tdTomato-FRT-WPRE-polyA cassette in the Rosa26 locus generated by homologous recombination.

Rats

hFcRn(SD)

Strain Name：SD-Fcgrtem1(hFCGRT)Smoc Strain State：Repository Live | Cat. NO.：NR-HU-200002
Validation Data：Presence

The endogenous rat Fcgrt gene was replaced by human FCGRT gene.

Rats

hALB(SD)

Strain Name：SD-Albem3(hALB)Smoc Strain State：Repository Live | Cat. NO.：NR-HU-200001
Validation Data：Presence

The endogenous rat Alb gene was replaced by human ALB gene.

Rats

hGCGR(SD)

Strain Name：SD-Gcgrem2(hGCGR)Smoc Strain State：Repository Live | Cat. NO.：NR-HU-225066
Validation Data：Presence

The endogenous rat Gcgr gene was replaced by human GCGR gene.

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