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Models

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Mice

H11-pThy1-hPSEN1-IRES-tdTomato

Strain Name：C57BL/6Smoc-Igs2em1(pThy1-PSEN1-IRES-tdTomato-WPRE-pA)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-KI-18049

A Thy1 promoter-PSEN1-IRES-tdTomato-WPRE-polyA cassette was knocked into the Igs2 locus (Hipp11 or H11; an intergenic region on chromosome 11 [cytoband A1 at ~3cM between the Eif4enif1 and Drg1 loci] reported to support high-level global gene expression in conjunction with the CAG (CAGGS) promoter and a higher rate of mitotic/interchromosomal recombination compared to Gt(ROSA)26Sor) .

Mice

H11-CAG-RSR-EYFP

Strain Name：C57BL/6Smoc-Igs2em1(CAG-RSR-EYFP)Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-KI-18056

A CAG-ROX-STOP-ROX-EYFP-V5tag-polyA conditional expression cassette was knocked into the Igs2 locus (Hipp11 or H11; an intergenic region on chromosome 11 [cytoband A1 at ~3cM between the Eif4enif1 and Drg1 loci] reported to support high-level global gene expression in conjunction with the CAG (CAGGS) promoter and a higher rate of mitotic/interchromosomal recombination compared to Gt(ROSA)26Sor) . This strain of mice can be used to mate with mice expressing the Dre recombinase. After exposure to Dre recombinase, expression of ellow fluorescent protein and V5 tag is observed for cell tracking.

Mice

Brs3-KO

Strain Name：C57BL/6Smoc-Brs3em1Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-KO-190608

Exon 2 of Brs3 gene was deleted to generate Brs3 knockout mice.

Rats

hGIPR(SD)

Strain Name：SD-Giprem1(hGIPR)Smoc Strain State：Repository Live | Cat. NO.：NR-HU-225067

The endogenous rat Gipr gene was replaced by human GIPR gene.

Rats

Tigre-TetO-Cre-IRES-EGFP(SD)

Strain Name：SD-lgs7em1(tetO-Cre-IRES-EGFP)Smoc Strain State：Embryo cryopreservation | Cat. NO.：NR-KI-200005

These rat harbor a tetO-Cre-IRES-EGFP cassette in the TIGRE locus generated by homologous recombination.

Rats

R26-CAG-LSL-Cas9-IRES-tdTomato(SD)

Strain Name：SD-Gt(ROSA)26Sorem1(CAG-LSL-Cas9-FRT-IRES-tdTomato-FRT-WPRE-polyA)Smoc Strain State：Repository Live | Cat. NO.：NR-KI-200004

These rats harbor a CAG-LSL-Cas9-FRT-IRES-tdTomato-FRT-WPRE-polyA cassette in the Rosa26 locus generated by homologous recombination.

Rats

hALB(SD)

Strain Name：SD-Albem3(hALB)Smoc Strain State：Repository Live | Cat. NO.：NR-HU-200001

The endogenous rat Alb gene was replaced by human ALB gene.

Rats

hFcRn(SD)

Strain Name：SD-Fcgrtem1(hFCGRT)Smoc Strain State：Repository Live | Cat. NO.：NR-HU-200002

The endogenous rat Fcgrt gene was replaced by human FCGRT gene.

Rats

hGCGR(SD)

Strain Name：SD-Gcgrem2(hGCGR)Smoc Strain State：Developing | Cat. NO.：NR-HU-225066

The endogenous rat Gcgr gene was replaced by human GCGR gene.

Rats

hAPP(SD)

Strain Name：SD-Appem1(hAPP)Smoc Strain State：Developing | Cat. NO.：NR-HU-225062

The endogenous rat App gene was replaced by human APP gene.

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