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Lsm5-KO

Strain Name：C57BL/6Smoc-Lsm5^em1Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-KO-190831

Exon 3-4 of Lsm5 gene was deleted to generate Lsm5 knockout mice.

Lix1l-KO

Strain Name：C57BL/6Smoc-Lix1L^em1Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-KO-190982

Exon 2 of Lix1l gene was deleted to generate Lix1l knockout mice.

Wwp1-KO

Strain Name：C57BL/6Smoc-Wwp1^em1Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-KO-190556

Exon 4 of Wwp1 gene was deleted to generate Wwp1 knockout mice.

Development of a heat shock inducible and inheritable RNAi system in silkworm

Model Organisms：家蚕 Product & Service：HSP70 Research field：Model

Transgenic silkworm RNAi Eclosion hormone

Conditional RNA interference achieved by Oct-1 POU/rtTA fusion protein activator and a modified TRE-mouse U6 promoter

Model Organisms：细胞 Product & Service：Palld Research field：Method

可逆性调节RNA干扰

Inducible microRNA-155 feedback promotes type I IFN signaling in antiviral innate immunity by targeting suppressor of...

Model Organisms：小鼠 Product & Service：Rig-I Research field：Immune system

RNA病毒感染

CKO mice developed by SMOC supported the identification of a novel lncRNA that regulates dendritic cell migration and the corresponding immune response

CKO mice lncRNA dendritic cell

These Mice Are About to Go Viral Because of the Nobel Prize!

microRNA (miRNA) microRNA mouse models Nobel Prize microRNA discovery genetically engineered mice miRNA in gene regulation miRNA therapeutics miRNA in cancer research customized mouse models contract research organization (CRO) preclinical drug discovery

The 2024 Nobel Prize in Physiology or Medicine awarded to Victor Ambros and Gary Ruvkun for their discovery of microRNA (miRNA) highlights its revolutionary role in gene regulation and disease treatment. This article explores miRNA's impact on neuroscience, cancer, and cardiovascular research. GenoBioTX offers advanced microRNA mouse models and customized genetic solutions, empowering researchers with essential tools to drive innovation in miRNA studies and therapeutic developments.

Zebrafish · Nematode

Provide services base on zebrafish and nematode research technology platform.

ゼブラフィッシュ

ゼブラフィッシュと線虫という二つの大小型モデル生物を保有しており、関連する技術サービスを提供することができます。