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Models

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Mice

Hras-Flox

Strain Name:C57BL/6Smoc-Hrasem1(flox)Smoc
Strain State:Developing | Cat. NO.:TBD

These mice carry loxP sites flanking target exons of Hras gene. When crossed with a Cre recombinase-expressing strain, this strain is useful in eliminating tissue-specific conditional expression of Hras gene.

Mice

Zfp143-KO

Strain Name:C57BL/6Smoc-Zfp143em1Smoc
Strain State:Developing | Cat. NO.:TBD

Exon 4-6 of Zfp143 gene was deleted to generate Zfp143 knockout mice.

Mice

Zfp143-Flox

Strain Name:C57BL/6Smoc-Zfp143em1(flox)Smoc
Strain State:Developing | Cat. NO.:TBD

These mice carry loxP sites flanking target exons of Zfp143 gene. When crossed with a Cre recombinase-expressing strain, this strain is useful in eliminating tissue-specific conditional expression of Zfp143 gene.

Mice

Rap1a-KO

Strain Name:C57BL/6Smoc-Rap1aem1Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-KO-190870

Exon 5-6 of Rap1a gene was deleted to generate Rap1a knockout mice.

Mice

Sema4b-KO

Strain Name:C57BL/6Smoc-Sema4bem1Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-KO-200474

Exon 3 of Sema4b gene was deleted to generate Sema4b knockout mice.

Mice

KPC(3)

Strain Name:C57BL/6Smoc-Krasem4(LSL-G12D)Trp53tm(LSL-R172H)Tg(Pdx1-Cre)Smoc
Strain State:Repository Live | Cat. NO.:NM-KI-234804

The Kras-LSL-G12D/Pdx1-Cre-Tg was crossed with Trp53-LSL-R172H to generate KPC(3) mice.

Cells

KrasG12D/Mki67-e(2A-tdtomato-2A-AKaluciferase)

Strain Name:KrasG12D/Mki67-e(2A-tdtomato-2A-AKaluciferase)
Strain State : Validation of target gene expression completed |  Cat. NO.:NM-YD10

derived from lung cancer model of the offspring produced by mating Mki67-tdTomato-2A-Luc (NM-KI-200223) and Kras-LSL-G12D mice (NM-KI-190003) infected by AAV-Cre virus

Cells

LKB1-KO/Kras-G12D-Luc

Strain Name:LKB1-KO/Kras-G12D-Luc
Strain State : Validation of tumorigenic capacity completed |  Cat. NO.:NM-YD07

derived from LKB1-KO/Kras-G12D-Luc mice spontaneous lung cancer model

Cells

Trp53-KO/Kras-G12D

Strain Name:Trp53-KO/Kras-G12D
Strain State : Validation of tumorigenic capacity completed |  Cat. NO.:NM-YD08

Trp53-KO/Kras-G12D cell line is murine cell derived from lung cancer model of the offspring produced by mating Trp53-Flox mice (NM-CKO-18005) and Kras-LSL-G12D mice (NM-KI-190003).

Cells

Smad4-Flox/Kras-LSL-G12D/Pdx1-Cre-Tg

Strain Name:Smad4-Flox/Kras-LSL-G12D/Pdx1-Cre-Tg
Strain State : 成瘤验证完成 |  Cat. NO.:NM-YD13

Derived from Smad4-Flox/Kras-LSL-G12D/Pdx1-Cre-Tg mice(NM-XA-234939) spontaneous lung cancer model

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