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Models

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Cells

R26-CAG-LSL-Kras*G12C-IRES-Luc(BABL/c)

Strain Name：R26-CAG-LSL-Kras*G12C-IRES-Luc(BABL/c)
Strain State ： 成瘤验证完成 |  Cat. NO.：NM-YD15

Derived from R26-CAG-LSL-Kras*G12C-IRES-Luc(BABL/c) mice(NM-KI-200324) spontaneous lung cancer model

Cells

KPC(R270H)

Strain Name：KPC(R270H)
Strain State ： Construction completed |  Cat. NO.：NM-YD11

The KPC(R270H) cell line was derived from the KPC(2) mice(NM-KI-220014)

Literature

The Kruppel-associated box repressor domain induces reversible and irreversible regulation of endogenous mouse genes...

Model Organisms：小鼠 Product & Service：Hprt Research field：Method

KRAB

Published date：2015-02-01 | References：Nucleic Acids Res

Literature

A pan-KRAS degrader for the treatment of KRAS-mutant cancers

Model Organisms：小鼠 Product & Service：- Research field：

Published date：2024-06-28 | References：Cell Discovery

Pages

SMOC Launched U-HuDTMbase®, Inclusive Resource Library of Innovative Therapeutic Target-Humanized Mouse Models, to Accelerate Novel Drug Discovery

U-HuDTMbase® is composed of more than 600 therapeutic target-humanized mouse models, including multiple background strains, and has covered almost all commonly studied areas, such as oncology, metabolism, immunity, inflammation and more.

Pages
Pages

Cancer Model

research on cancer cancer model mouse models of cancer

The laboratory mouse is widely considered as a valid and affordable model organism for studying human disease. Mouse models of cancer not only enable researchers to understand the genetic basis of tumor development in complicated and dynamic physiological systems, but also serve as irreplaceable tools for developing and testing new therapies.  Shanghai Model Organisms Center offers a variety of mouse models of cancer to meet the needs of both academic and industry partners.

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