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Models

About 45 results
Mice

Lair1-KO

Strain Name：C57BL/6Smoc-Lair1em1Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-KO-200323

Exon 3-7 of Lair1 gene was deleted to generate Lair1 knockout mice.

Mice

Ace2-KO

Strain Name：C57BL/6Smoc-Ace2em1Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-KO-190906

exon 3-7 of Ace2 gene was deleted to generate Ace2 knockout mice.

Mice

Lair1-Flox

Strain Name：C57BL/6Smoc-Lair1em1(flox)Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-CKO-200193

These mice carry loxP sites flanking exon 4-8 of Lair1 gene. When crossed with a Cre recombinase-expressing strain, this strain is useful in eliminating tissue-specific conditional expression of Lair1 gene.

Mice

Trpv2-Flox

Strain Name：B6;129S-Trpv2tm1(flox)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-CKO-00023

Mice homozygous for a knock-out allele exhibit impaired macrophage migration, binding, and phagocytosis with increased susceptiblity and mortality following bacterial infection.

Mice

Ace2-2A-CreERT2

Strain Name：C57BL/6Smoc-Ace2em2(2A-CreERT2-WPRE-polyA)Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-KI-200187

A 2A-CreERT2-WPRE-polyA expression cassette was knocked into the Ace2 gene stop codon site. Ace2 encodes angiotensin I converting enzyme 2. When crossed with a strain carrying a gene flanked by loxP sites, the flanked gene will be removed in cells expressing Cre. This strain is useful for studying lung injury and kidney disease caused by SARS coronavirus infection.

Mice

hCD81

Strain Name：C57BL/6Smoc-Cd81em1(CD81)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-190041

The endogenous mouse Cd81 gene was replaced by human CD81 gene.

Mice

hCD81/hOCLN

Strain Name：C57BL/6Smoc-Cd81em1(hCD81)Oclnem1(hOCLN)Smoc
Strain State：Repository Live | Cat. NO.：NM-HU-2000107

These mice are obtained through breeding of two single gene humanized mice.

Mice

hDPP4

Strain Name：C57BL/6Smoc-Dpp4em1(DPP4)Smoc
Strain State：Repository Live | Cat. NO.：NM-HU-190042

The endogenous mouse Dpp4 gene was replaced by human DPP4 gene.

Mice

hOCLN

Strain Name：C57BL/6Smoc-Oclnem1(hOCLN)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-190072

The endogenous mouse Ocln gene was replaced by human OCLN gene.

Mice

H11-pAlb-NTCP-C9-IRES-EGFP

Strain Name：C57BL/6Smoc-Igs2em1(2xins-Alb-NTCP-C9 tag-IRES-EGFP-Wpre-pA-2xIns)Smoc
Strain State：Repository Live | Cat. NO.：NM-KI-200054

These mice harbor a 2xins-Alb-NTCP-C9 tag-IRES-EGFP-Wpre-pA-2xIns cassette in the lgs2 locus generated by homologous recombination.

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