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Models

About 234 results
Mice

hIL6

Strain Name：C57BL/6Smoc-Il6tm1(hIL6)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-18017

This IL6 humanized mouse model was established by replacing the mouse Il6 gene coding exon1-5 and introns with the human IL6 corresponding sequence by homologous recombination via ES cell targeting.

Mice

NMG

Strain Name：NOD.Cg-PrkdcscidIl2rgem1Smoc
Strain State：Repository Live | Cat. NO.：NM-NSG-001

Prkdc and Il2rg genes were both knocked-out in NOD mice.  Lacking mature T, B and NK cells Low immune rejection against human cells and tissues Good tumorigenicity so that a small number of cells can form tumors. Significant improvement in the survival of transplanted human cells and tissues Suitable for the transplantation of human hematopoietic stem cells and the preparation of humanized mouse models Suitable as the carrier mice for the transplantation of heterologous cells and tissues

Mice

hFCRN

Strain Name：C57BL/6Smoc-Gt(ROSA)26Sorem1(CAG-hFcRn)Fcgrtem1/Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-00109

This FcRn humanized strain is established by mating endogenous mouse Fcgrt gene Knockout mice with R26-hFcRn(FCGRT) Knock-in mice. These FcRn humanized mouse models can be useful for evalueting the efficacy of potential immunotherapy drug combinations. While hFCRN(2)(Stock No.NM-HU-190070) and hFCRN(3)(Stock No.NM-HU-2000032）mice function similarly to hFCRN mice,for more detailed information please contact our technical advisor.

Mice

hIL2 SP-hIL15-Tg(NMG)

Strain Name：NOD-PrkdcscidIl2rgem1Tg(hIL2 SP-hIL15)Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-KI-220133

These transgenic mice carry humanized IL15.

Mice

hIL5-Tg(NMG,2)

Strain Name：NOD-PrkdcscidIl2rgem2Tg(hIL5)Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-KI-220131

These transgenic mice carry humanized IL5.While hIL5-Tg(NMG)(Stock No.NM-KI-215005) mice function similarly to hIL5-Tg(NMG)(2) mice, for more detailed information please contact our technical advisor.

Mice

hIL4-Tg(NMG)

Strain Name：NOD-PrkdcscidIl2rgem1Tg(hIL4)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-KI-215004

These transgenic mice carry humanized IL4.

Mice

hIL2-Tg(NMG)

Strain Name：NOD-PrkdcscidIl2rgem1Tg(hIL2)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-NSG-010

These transgenic mice carry humanized IL2.

Mice

hIL3-hCSF2-Tg(NMG)

Strain Name：NOD-PrkdcscidIl2rgem1Tg(hIL3-hCSF2)Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-KI-215006

These transgenic mice carry humanized IL3 and humanized CSF2.

Mice

hB7H4

Strain Name：C57BL/6Smoc-Vtcn1em1(hVTCN1)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-190004

This VTCN1 humanized mouse model was established by replacing the mouse Vtcn1 gene with the human VTCN1. While hB7H4(2)(Stock No.NM-HU-190075) mice function similarly to hB7H4 mice,for more detailed information please contact our technical advisor.

Mice

hTLR9

Strain Name：C57BL/6Smoc-Tlr9tm1(hTLR9)Smoc
Strain State：Repository Live | Cat. NO.：NM-HU-18016

This TLR9 humanized mouse model was established by replacing the mouse Tlr9 gene exon2 with the human TLR9 corresponding sequence by homologous recombination.

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