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Models

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Mice

Gabrr1-KO

Strain Name:C57BL/6Smoc-Gabrr1em1Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-KO-190580

Exon 3 of Gabrr1 gene was deleted to generate Gabrr1 knockout mice.

Mice

Gabrr1-Flox

Strain Name:C57BL/6Smoc-Gabrr1em1(flox)Smoc
Strain State:Developing | Cat. NO.:TBD

These mice carry loxP sites flanking target exons of Gabrr1 gene. When crossed with a Cre recombinase-expressing strain, this strain is useful in eliminating tissue-specific conditional expression of Gabrr1 gene.

Mice

Gabrg2-KO

Strain Name:C57BL/6Smoc-Gabrg2em1Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-KO-190577

Exon 2 of Gabrg2 gene was deleted to generate Gabrg2 knockout mice.

Mice

Gabra6-KO

Strain Name:C57BL/6Smoc-Gabra6em1Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-KO-190574

Exon 2 of Gabra6 gene was deleted to generate Gabra6 knockout mice.

Mice

Gabra6-Flox

Strain Name:C57BL/6Smoc-Gabra6em1(flox)Smoc
Strain State:Developing | Cat. NO.:TBD

These mice carry loxP sites flanking target exons of Gabra6 gene. When crossed with a Cre recombinase-expressing strain, this strain is useful in eliminating tissue-specific conditional expression of Gabra6 gene.

Mice

Slc6a11-CreERT2

Strain Name:C57BL/6Smoc-Slc6a11em1(CreERT2-polyA(SV40)Smoc
Strain State:Sperm cryopreservation | Cat. NO.:NM-KI-200130

A CreERT2-polyA expression cassette was knocked into the Slc6a11 gene start codon site. Slc6a11 encodes GAT3 (Gabt4), a sodium-dependent transporter that uptakes the inhibitory neurotransmitter gamma-aminobutyric acid (GABA), which ends the GABA neurotransmission. When Slc6a11-CreERT2 mice are bred with mice containing loxP-flanked sequence, tamoxifen-inducible, Cre-mediated recombination will result in deletion of the floxed sequences in SLC6A11positive cells. Defects in Slc6a11 may result in epilepsy or behavioral and intellectual defects.

Mice

Gabrq-KO

Strain Name:C57BL/6Smoc-Gabrqem1Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-KO-190579

Exon 3 of Gabrq gene was deleted to generate Gabrq knockout mice.

Mice

Gabre-KO

Strain Name:C57BL/6Smoc-Gabreem1Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-KO-190576

Exon 2 of Gabre gene was deleted to generate Gabre knockout mice.

Mice

Gabrg3-KO

Strain Name:C57BL/6Smoc-Gabrg3em1Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-KO-190578

Exon 3 of Gabrg3 gene was deleted to generate Gabrg3 knockout mice.

Mice

Slc32a1-IRES-Cre

Strain Name:C57BL/6Smoc-Slc32a1em1(IRES-iCre)Smoc
Strain State:Repository Live | Cat. NO.:NM-KI-200081

A IRES-iCre expression cassette was knocked into the Slc32a1 gene stop codon site.

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