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Models

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Mice

NMG

Strain Name：NOD.Cg-PrkdcscidIl2rgem1Smoc
Strain State：Repository Live | Cat. NO.：NM-NSG-001

Prkdc and Il2rg genes were both knocked-out in NOD mice.  Lacking mature T, B and NK cells Low immune rejection against human cells and tissues Good tumorigenicity so that a small number of cells can form tumors. Significant improvement in the survival of transplanted human cells and tissues Suitable for the transplantation of human hematopoietic stem cells and the preparation of humanized mouse models Suitable as the carrier mice for the transplantation of heterologous cells and tissues

Mice

hIL2RG/hIL2RB

Strain Name：C57BL/6Smoc-Il2rgem1(IL2RG)Il2rbtm1(hIL2RB)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-210354

hIL2RG(NM-HU-200007) was crossed with hIL2RB(NM-HU-2000055) to generate hIL2RG/hIL2RB mice.

Mice

hIL2RG

Strain Name：C57BL/6Smoc-Il2rgem1(IL2RG)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-200007

The endogenous mouse Il2rg gene was replaced by human IL2RG gene.

Mice

Adgra2-Flox

Strain Name：B6;129S-Adgra2tm1(flox)Smoc
Strain State：Repository Live | Cat. NO.：NM-CKO-00101

These Gpr124 flox mutant mice possess loxP sites flanking exon 2 of the G protein-coupled receptor 124 (Gpr124) targeted gene. Homozygotes are viable, fertile, normal in size and do not display any gross physical or behavioral abnormalities.

Mice

Il2rg-KO

Strain Name：C57BL/6Smoc-Il2rgem1Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-KO-210098

Exon 2 of Il2rg gene was deleted to generate Il2rg knockout mice.

Mice

Il2rg-Flox

Strain Name：C57BL/6Smoc-Il2rgem1(flox)Smoc
Strain State：Developing | Cat. NO.：TBD

These mice carry loxP sites flanking target exons of Il2rg gene. When crossed with a Cre recombinase-expressing strain, this strain is useful in eliminating tissue-specific conditional expression of Il2rg gene.

Mice

Htr1a-KO

Strain Name：C57BL/6Smoc-Htr1Aem1Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-KO-190594

Exon 1 of Htr1a gene was deleted to generate Htr1a knockout mice.

Mice

Cebpg-Flox

Strain Name：C57BL/6Smoc-Cebpgem1(flox)Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-CKO-241154

These strains carry loxP sites flanking exon 2 of Cebpg gene. When crossed with a Cre recombinase-expressing strain, this strain is useful in eliminating tissue-specific conditional expression of Cebpg gene.

Mice

Cebpg-KO

Strain Name：C57BL/6Smoc-Cebpgem1Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-KO-201465

Exon 2 of Cebpg gene was deleted to generate Cebpg knockout mice.

Mice

hSIGLEC10

Strain Name：C57BL/6Smoc-Siglecgtm1(hSIGLEC10)/Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-2000061

The endogenous mouse Siglecg gene was replaced by human SIGLEC10 gene.

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