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Models

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Mice

Grik5-KO

Strain Name：C57BL/6Smoc-Grik5em1Smoc
Strain State：Repository Live | Cat. NO.：NM-KO-190586

Exon 4-6 of Grik5 gene was deleted to generate Grik5 knockout mice.

Mice

Grik4-KO

Strain Name：C57BL/6Smoc-Grik4em1Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-KO-190585

Exon 5 of Grik4 gene was deleted to generate Grik4 knockout mice.

Mice

Gpr65-IRES-Cre

Strain Name：C57BL/6Smoc-Gpr65em1(IRES-iCre)Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-KI-200135

A IRES-iCre expression cassette was knocked into the Gpr65 gene stop codon site.

Mice

Gna11-Flox

Strain Name：C57BL/6Smoc-Gna11em1(flox)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-CKO-205090

These mice carry loxP sites flanking exon 2 of Gna11 gene. When crossed with a Cre recombinase-expressing strain, this strain is useful in eliminating tissue-specific conditional expression of Gna11 gene.

Mice

Gpr156-Flox

Strain Name：B6;129S-Gpr156tm1(flox)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-CKO-00099

These Gpr156 flox mice possess loxP sites flanking exons 2-3 of the G protein-coupled receptor 156 (Gpr156) gene. When crossed with a Cre recombinase-expressing strain, this strain is useful in eliminating tissue-specific conditional expression of the gene.

Mice

hAppNL-G-F

Strain Name：C57BL/6Smoc-Apptm3(hAppNL-G-F)/Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-2000088

The endogenous mouse App gene was replaced by human AppNL-G-F.

Mice

hAppNL-G-F/hAPOE4

Strain Name：C57BL/6Smoc-Apptm3(hAppNL-G-F)Apoetm2(hAPOE4)Smoc
Strain State：Repository Live | Cat. NO.：NM-XA-250109

The hAPOE4(NM-HU-190002) was crossed with hAppNL-G-F(NM-HU-2000088) to generate hAppNL-G-F/hAPOE4 mice.

Mice

HLA-G/B2M

Strain Name：C57BL/6Smoc-B2mem1(hB2M-2A-HLA-G)Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-HU-241967

The endogenous mouse B2m gene was replaced by human B2M/HLA-G gene.

Mice

Lepr-g.G109052T

Strain Name：B6.129S-Leprtm1Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-KI-00001

A point mutation was introduced to exon 19 (c.109052 G>T) via a recombineering strategy. Homozygous mutants are hyperphagic, low-activity, poorly cold-adapted, sterile and have enhanced fat conversion.

Mice

Mapt-hMAPT-P301S/hAppNL-G-F

Strain Name：C57BL/6Smoc-Maptem1hMAPT-P301SApptm3(hAppNL-G-F)Smoc
Strain State：Developing | Cat. NO.：NM-XA-250110

The hMAPT-P301S(NM-KI-233262) was crossed with hAppNL-G-F(NM-HU-2000088) to generate Mapt-hMAPT-P301S/hAppNL-G-F mice.

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