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Models

About 103 results
Mice

NOD SCID

Strain Name：NOD.Cg-Prkdcscid/NifdcSmoc
Strain State：Repository Live | Cat. NO.：SM-019

The scid mutation has been transferred onto a diabetes-susceptible Non-Obese Diabetic (NOD) background. NOD-Scid mice do not develop diabetes, lack T and B cells, and are inherently immune deficient, making them good recipients for transplantation of human hematopoietic stem cells and human solid tumors. 

Mice

Foxp3-IRES-tdTomato-2A-Cre

Strain Name：C57BL/6Smoc-Foxp3em3(IRES-tdTomato-2A-iCre)Smoc
Strain State：Repository Live | Cat. NO.：NM-KI-190119

A IRES-tdTomato-2A-Cre expression cassette was knocked into the Foxp3 gene stop codon site. This strain is useful in studying regulatory T cell in autoimmunity, especially in type 1 diabetes.

Mice

C57BL/6

Strain Name：C57BL/6Smoc
Strain State：Repository Live | Cat. NO.：SM-001

C57BL/6 mice have a high reproductive capacity, a long life span, and a low tumor susceptibility. Male mice are aggressive and fight frequently. Diet can cause obesity, type II diabetes, and atherosclerosis in these mice. The C57BL/6 mouse is the first to have its entire genome sequenced. It is the most extensively used inbred mouse strain as a genetic basis for congenic and mutant mice. It is also used in genetics, metabolism, immunology, neurology, behavioral research, pharmacodynamics, and medication safety evaluation.

Mice

Cpe-KO

Strain Name：C57BL/6Smoc-Cpeem1Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-KO-190671

Exon 2 of Cpe gene was deleted to generate Cpe knockout mice.

Mice

Iapp-KO

Strain Name：C57BL/6Smoc-Iappem1Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-KO-190664

Exon 3 of Iapp gene was deleted to generate Iapp knockout mice.

Mice

Adipor2-KO

Strain Name：C57BL/6Smoc-Adipor2em1Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-KO-190667

Exon 3-4 of Adipor2 gene was deleted to generate Adipor2 knockout mice.

Mice

Mapk8-KO

Strain Name：C57BL/6Smoc-Mapk8em1Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-KO-190836

Exon 3 of Mapk8 gene was deleted to generate Mapk8 knockout mice.

Mice

Atxn2-KO

Strain Name：C57BL/6Smoc-Atxn2em1Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-KO-190920

Exon 6 of Atxn2 gene was deleted to generate Atxn2 knockout mice.

Mice

Fto-Flox

Strain Name：C57BL/6Smoc-Ftoem3(flox)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-CKO-190005

These mice carry loxP sites flanking exon3 of Fto gene. When crossed with a Cre recombinase-expressing strain, this strain is useful in eliminating tissue-specific conditional expression of Fto gene.

Mice

R26-CAG-LSL-Fto-IRES-EGFP

Strain Name：C57BL/6Smoc-Gt(ROSA)26Sorem1(CAG-LSL-3xFLAG-Fto-IRES-EGFP)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-KI-190055

These mice harbor a CAG-LSL-3xFLAG-Fto-IRES-EGFP cassette in the Rosa26 locus generated by homologous recombination.

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