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Fto-Flox

Strain Name：C57BL/6Smoc-Fto^{em3(flox)Smoc}
Strain State：Embryo cryopreservation | Cat. NO.：NM-CKO-190005

These mice carry loxP sites flanking exon3 of Fto gene. When crossed with a Cre recombinase-expressing strain, this strain is useful in eliminating tissue-specific conditional expression of Fto gene.

R26-CAG-LSL-Fto-IRES-EGFP

Strain Name：C57BL/6Smoc-Gt(ROSA)26Sor^{em1(CAG-LSL-3xFLAG-Fto-IRES-EGFP)Smoc}
Strain State：Embryo cryopreservation | Cat. NO.：NM-KI-190055

These mice harbor a CAG-LSL-3xFLAG-Fto-IRES-EGFP cassette in the Rosa26 locus generated by homologous recombination.

Lcn6-Flox

Strain Name：B6;129S-Lcn6^{tm1(flox)Smoc}
Strain State：Embryo cryopreservation | Cat. NO.：NM-CKO-00109

These mice carry loxP sites flanking exon 2 of Lcn6 gene. When crossed with a Cre recombinase-expressing strain, this strain is useful in eliminating tissue-specific conditional expression of Lcn6 gene.

Tnfsf4-KO

Strain Name：C57BL/6Smoc-Tnfsf4^em2Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-KO-190889

Exon 2 of Tnfsf4 gene was deleted to generate Tnfsf4 knockout mice.

Lep-KO(SD)

Strain Name：SD-Lep^em1Smoc Strain State：Repository Live | Cat. NO.：NR-KO-200001

Exon 2-3 of Lep gene was deleted to generate Lep knockout rat.

Abcb4-KO(SD)

Strain Name：SD-Abcb4^em1Smoc Strain State：Repository Live | Cat. NO.：NR-KO-190006

Abcb4-201 exon 1-28 and Abcb4-203 exon 1-28 of Abcb4 gene was deleted to generate Abcb4 knockout rat.

Swimming Exercise Protects against Insulin Resistance viaRegulating Oxidative Stress through Nox4 and AKT Signaling...

Model Organisms：Mouse Product & Service：m-hNox4 Research field：Diabetes

Diabetes

Gain-of-Function Mutations of SLC16A11 Contribute to the Pathogenesis of Type 2 Diabetes

Model Organisms：Mouse Product & Service：Slc16a11 Research field：Diabetes

Targeting long noncoding RNA-AQP4-AS1 for the treatment of retinal neurovascular dysfunction in diabetes mellitus

Model Organisms：小鼠 Product & Service：Aqp4-KO Research field：Diabetic retinopathy

Endocrinology and Metabolism

Diabetic mouse model type 2 diabetes mouse model

Long-term feeding of high-fat diets can cause obesity and increased fasting blood glucose in mice along with fat accumulation and insulin resistance in the body to mimic human type II diabetes.