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Lcn6-Flox

Strain Name：B6;129S-Lcn6^{tm1(flox)Smoc}
Strain State：Embryo cryopreservation | Cat. NO.：NM-CKO-00109

These mice carry loxP sites flanking exon 2 of Lcn6 gene. When crossed with a Cre recombinase-expressing strain, this strain is useful in eliminating tissue-specific conditional expression of Lcn6 gene.

Tnfsf4-KO

Strain Name：C57BL/6Smoc-Tnfsf4^em2Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-KO-190889

Exon 2 of Tnfsf4 gene was deleted to generate Tnfsf4 knockout mice.

Lep-KO(SD)

Strain Name：SD-Lep^em1Smoc Strain State：Repository Live | Cat. NO.：NR-KO-200001

Exon 2-3 of Lep gene was deleted to generate Lep knockout rat.

Abcb4-KO(SD)

Strain Name：SD-Abcb4^em1Smoc Strain State：Repository Live | Cat. NO.：NR-KO-190006

Abcb4-201 exon 1-28 and Abcb4-203 exon 1-28 of Abcb4 gene was deleted to generate Abcb4 knockout rat.

Swimming Exercise Protects against Insulin Resistance viaRegulating Oxidative Stress through Nox4 and AKT Signaling...

Model Organisms：Mouse Product & Service：m-hNox4 Research field：Diabetes

Diabetes

Gain-of-Function Mutations of SLC16A11 Contribute to the Pathogenesis of Type 2 Diabetes

Model Organisms：Mouse Product & Service：Slc16a11 Research field：Diabetes

Targeting long noncoding RNA-AQP4-AS1 for the treatment of retinal neurovascular dysfunction in diabetes mellitus

Model Organisms：小鼠 Product & Service：Aqp4-KO Research field：Diabetic retinopathy

Endocrinology and Metabolism

Diabetic mouse model type 2 diabetes mouse model

Long-term feeding of high-fat diets can cause obesity and increased fasting blood glucose in mice along with fat accumulation and insulin resistance in the body to mimic human type II diabetes.

Metabolic Analysis

Metabolic analysis

There are many mice models used to mimic human metabolic diseases, such as diabetes and obesity, which are caused by nutritional imbalances and metabolic disorders. The detection and analysis of sugar and lipid metabolism phenotypes in these model mice are crucial for the establishment of model mice, the study of disease progression, and the research on the pathogenesis. Shanghai Model Organisms can help your research on metabolism by providing you with a series of testing tools for glucose and lipid metabolisms.

Excision and Regeneration of Tissue

liver regeneration subtotal gastrectomy

A mouse tissue regeneration model can be established by an operation of partial tissue excision. Such models can be used to study the changes in morphology, serology and metabolism during tissue regeneration, and hence lay the experimental foundation for studying the mechanisms regulating tissue regeneration.