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Models

About 65 results
Mice

Tmem67-KO

Strain Name：C57BL/6Smoc-Tmem67em1Smoc
Strain State：Developing | Cat. NO.：NM-KO-242378

The exon 3-12 of Tmem67 gene was deleted to generate Tmem67 knockout mouse. There have been reports of deaths caused by genetic modification. For details, click on the MGI ID in the genetic information.

Mice

Dna2-KO

Strain Name：C57BL/6Smoc-Dna2em1Smoc
Strain State：Developing | Cat. NO.：NM-KO-250724

The exon 4-7 of Dna2 gene was deleted to generate Dna2 knockout mouse. There have been reports of deaths caused by genetic modification. For details, click on the MGI ID in the genetic information.

Mice

Slc4a1-KO

Strain Name：C57BL/6Smoc-Slc4a1em1Smoc
Strain State：Developing | Cat. NO.：NM-KO-242564

The exon 2-20 of Slc4a1 gene was deleted to generate Slc4a1 knockout mouse. There have been reports of deaths caused by genetic modification. For details, click on the MGI ID in the genetic information.

Mice

Ahr-KO

Strain Name：C57BL/6Smoc-Ahrem1Smoc
Strain State：Repository Live | Cat. NO.：NM-KO-18008

Exon3 of Ahr gene was deleted to generate Ahr knockout mice. The homozygous female mice of this strain had impaired fertility. There have been reports of deaths caused by genetic modification. For details, click on the MGI ID in the genetic information.

Mice

F9-KO

Strain Name：C57BL/6Smoc-F9em1Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-KO-18046

The F9 gene is located on the X chromosome. In this F9 knockout mouse model, gRNAs were designed targeting Exon8 of F9 gene via CRISPR gene editing technology. Loss of F9 caused coagulopathy in mice. Mice that are homozygous for F9 knockout are viable, fertile and normal in size. Normal fighting in the cage may cause bleeding or even death due to massive internal hemorrhaging. After the tail cutting, wounds must be cauterized to prevent homozygous knockout mice from blood loss and death. This strain is a powerful model for studying coagulopathy, gene therapy methods and function of factor IX mutations. F9-KO mice (Stock No.NM-KO-18046）carry a knockout allele derived from the targeted deletion of exon 8. While F9-KO(2) mice (Stock No.NM-KO-200607) carrying the exon 1-8 deletion.

Mice

Tradd-KO

Strain Name：C57BL/6Smoc-Traddem1Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-KO-191169

Exon 2-5 of Tradd gene was deleted to generate Tradd knockout mice.

Mice

Casp1-KO

Strain Name：C57BL/6Smoc-Casp1em1Smoc
Strain State：Repository Live | Cat. NO.：NM-KO-190443

exon 2-4 of Casp1 gene was deleted to generate Casp1 knockout mice.

Mice

Lmx1b-Flox

Strain Name：C57BL/6Smoc-Lmx1bem1(flox)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-CKO-200117

These mice carry loxP sites flanking exon 4-6 of Lmx1b gene. When crossed with a Cre recombinase-expressing strain, this strain is useful in eliminating tissue-specific conditional expression of Lmx1b gene.

Mice

Plp1-Flox

Strain Name：C57BL/6Smoc-Plp1em1(flox)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-CKO-200072

These mice carry loxP sites flanking exon 3 of Plp1 gene. When crossed with a Cre recombinase-expressing strain, this strain is useful in eliminating tissue-specific conditional expression of Plp1 gene.

Mice

Faf1-KO

Strain Name：C57BL/6Smoc-Faf1em1Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-KO-191163

Exon 3 of Faf1 gene was deleted to generate Faf1 knockout mice.

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