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Models

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Mice

Khdrbs1-KO

Strain Name：C57BL/6Smoc-Khdrbs1em1Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-KO-251777

The exon 4-5 of Khdrbs1 gene was deleted to generate Khdrbs1 knockout mouse. There have been reports of deaths caused by genetic modification. For details, click on the MGI ID in the genetic information.

Mice

Son-KO

Strain Name：C57BL/6Smoc-Sonem1Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-KO-242049

The exon 2-9 of Son gene was deleted to generate Son knockout mouse. There have been reports of deaths caused by genetic modification. For details, click on the MGI ID in the genetic information.

Mice

Nle1-KO

Strain Name：C57BL/6Smoc-Nle1em1Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-KO-242814

The exon 2-3 of Nle1 gene was deleted to generate Nle1 knockout mouse. There have been reports of deaths caused by genetic modification. For details, click on the MGI ID in the genetic information.

Mice

Slc4a1-KO

Strain Name：C57BL/6Smoc-Slc4a1em1Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-KO-242564

The exon 2-20 of Slc4a1 gene was deleted to generate Slc4a1 knockout mouse. There have been reports of deaths caused by genetic modification. For details, click on the MGI ID in the genetic information.

Mice

Tmem67-KO

Strain Name：C57BL/6Smoc-Tmem67em1Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-KO-242378

The exon 3-12 of Tmem67 gene was deleted to generate Tmem67 knockout mouse. There have been reports of deaths caused by genetic modification. For details, click on the MGI ID in the genetic information.

Mice

Dna2-KO

Strain Name：C57BL/6Smoc-Dna2em1Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-KO-250724

The exon 4-7 of Dna2 gene was deleted to generate Dna2 knockout mouse. There have been reports of deaths caused by genetic modification. For details, click on the MGI ID in the genetic information.

Mice

Brpf3-KO

Strain Name：C57BL/6Smoc-Brpf3em1Smoc
Strain State：Repository Live | Cat. NO.：NM-KO-242661

The exon 5-7 of Brpf3 gene was deleted to generate Brpf3 knockout mouse. There have been reports of deaths caused by genetic modification.

Mice

Ahr-KO

Strain Name：C57BL/6Smoc-Ahrem1Smoc
Strain State：Repository Live | Cat. NO.：NM-KO-18008

Exon3 of Ahr gene was deleted to generate Ahr knockout mice. The homozygous female mice of this strain had impaired fertility. There have been reports of deaths caused by genetic modification. For details, click on the MGI ID in the genetic information.

Mice

F9-KO

Strain Name：C57BL/6Smoc-F9em1Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-KO-18046
Validation Data：Presence  |  Publications：1piece

The F9 gene is located on the X chromosome. In this F9 knockout mouse model, gRNAs were designed targeting Exon8 of F9 gene via CRISPR gene editing technology. Loss of F9 caused coagulopathy in mice. Mice that are homozygous for F9 knockout are viable, fertile and normal in size. Normal fighting in the cage may cause bleeding or even death due to massive internal hemorrhaging. After the tail cutting, wounds must be cauterized to prevent homozygous knockout mice from blood loss and death. This strain is a powerful model for studying coagulopathy, gene therapy methods and function of factor IX mutations. F9-KO mice (Stock No.NM-KO-18046）carry a knockout allele derived from the targeted deletion of exon 8. While F9-KO(2) mice (Stock No.NM-KO-200607) carrying the exon 1-8 deletion.

Mice

Pah-KO

Strain Name：C57BL/6Smoc-Pahem1Smoc
Strain State：Repository Live | Cat. NO.：NM-KO-2110565
Validation Data：Presence

Exon 2-5 of pah gene was deleted to generate pah knockout mice. The homozygous (HO) mice have a certain mortality rate (approximately 15%). Heterozygous (HE) mice are recommended for colony establishment. If you need to purchase homozygous (HO) mice directly for experiments, it is recommended to purchase an additional 15%-20% to avoid mouse death affecting subsequent experiments.

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