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Mice

Opn4-Cre

Strain Name:C57BL/6Smoc-Opn4em1(Cre-WPRE-polyA)Smoc
Strain State:Sperm cryopreservation | Cat. NO.:NM-KI-200304
Validation Data:Presence

Cre-WPRE-polyA expression cassette was knocked into the Opn4 gene start codon site. The melanopsin gene (Opn4) encodes a functional photopigment. When crossed with a strain carrying a gene flanked by loxP sites, the flanked gene will be removed in cells expressing cre. This strain may be useful for studying circadian rhythm regulation.

Mice

Notch1-CreERT2

Strain Name:C57BL/6Smoc-Notch1em1(CreERT2-2xpA)Smoc
Strain State:Sperm cryopreservation | Cat. NO.:NM-KI-200122
Validation Data:Presence

A CreERT2-2xpA expression cassette was knocked into the Notch1 gene start codon site. Notch1 performs vital cell functions, such as proliferation, differentiation, apoptosis, and stem cell maintenance. When Notch1-CreERT2 mice are bred with mice containing loxP-flanked sequence, tamoxifen-inducible, Cre-mediated recombination will result in deletion of the floxed sequences in NOTCH1 positive cells.

Mice

Cspg4-CreERT2-2A

Strain Name:C57BL/6Smoc-Cspg4em(CreERT2-P2A)1Smoc
Strain State:Sperm cryopreservation | Cat. NO.:NM-KI-225033
Validation Data:Presence

CreERT2-P2A expression cassette was knocked into the Cspg4 gene .

Mice

Slc6a4-Cre

Strain Name:C57BL/6Smoc-Slc6a4em1(iCre-pA)Smoc
Strain State:Sperm cryopreservation | Cat. NO.:NM-KI-200115
Validation Data:Presence

A iCre-pA expression cassette was knocked into the Slc6a4 gene start codon site. When crossed with a strain carrying a gene flanked by loxP sites, the flanked gene will be removed in cells expressing Cre. The gene product has been involved in the neurological disorders such as addiction and depression.

Mice

Lyz2-CreERT2-IRES-EGFP

Strain Name:C57BL/6Smoc-Lyz2em2(CreERT2-IRES-EGFP)Smoc
Strain State:Repository Live | Cat. NO.:NM-KI-18047
Validation Data:Presence

A Kozak-CreERT2-IRES-EGFP expression cassette was knocked into the Lyz2 gene start codon site by homologous recombination.

Mice

Prom1-CreERT2

Strain Name:C57BL/6Smoc-Prom1em1(CreERT2-PolyA)Smoc
Strain State:Sperm cryopreservation | Cat. NO.:NM-KI-200169
Validation Data:Presence

A CreERT2-PolyA expression cassette was knocked into the Prom1 gene start codon site. Prom1 encodes a pentaspan transmembrane glycoprotein. The protein localizes to membrane protrusions and is often expressed on adult stem cells, where it is thought to function in maintaining stem cell properties by suppressing differentiation. When these Prom1-CreERT2 mice are bred with mice containing a loxP-flanked sequence of interest, tamoxifen-inducible, Cre-mediated recombination will result in deletion of the flanked sequences in Prom1 expressing cells.

Mice

Vim-Cre

Strain Name:C57BL/6Smoc-Vimem(Kozak-Cre-WPRE-pA)Smoc
Strain State:Sperm cryopreservation | Cat. NO.:NM-KI-220105

Kozak-Cre-WPRE-pA expression cassette was knocked into the Vim gene start codon site.

Mice

Ltf-Cre-IRES-tdTomato

Strain Name:C57BL/6Smoc-Ltfem1(iCre-IRES-tdTomato-WPRE-pA)Smoc
Strain State:Sperm cryopreservation | Cat. NO.:NM-KI-200116
Validation Data:Presence

A iCre-IRES-tdTomato-WPRE-pA expression cassette was knocked into the Ltf gene start codon site.

Mice

Tff1-Cre

Strain Name:C57BL/6Smoc-Tff1em(Cre)1Smoc
Strain State:Sperm cryopreservation | Cat. NO.:NM-KI-225005
Validation Data:Presence

Cre expression cassette was knocked into the Tff1 gene .

Mice

Cdh6-CreERT2

Strain Name:C57BL/6Smoc-Cdh6em1(CreERT2-WPRE-polyA)Smoc
Strain State:Sperm cryopreservation | Cat. NO.:NM-KI-200140

A CreERT2-WPRE-polyA expression cassette was knocked into the Cdh6 gene start codon site.

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