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Models

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Mice

hPD-1/Cd8a-IRES-Akaluc-2A-EGFP

Strain Name:C57BL/6Smoc-Pdcd1tm1(hPDCD1)Cd8atm1(V5-IRES-Akaluc-2A-EGFP)Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-HU-210373

hPD-1(NM-HU-00015) was crossed with Cd8a-IRES-Luc-2A-EGFP(NM-KI-18030) to generate hPD-1/Cd8a-IRES-Luc-2A-EGFP mice

Mice

hTFR1

Strain Name:C57BL/6Smoc-Tfrctm1(hTFRC)Smoc
Strain State:Repository Live | Cat. NO.:NM-HU-215059
Validation Data:Presence

The endogenous mouse Tfrc gene was replaced by human TFRC gene.

Mice

hCD38(2)

Strain Name:C57BL/6Smoc-Cd38tm2(CD38)Smoc
Strain State:Repository Live | Cat. NO.:NM-HU-190059
Validation Data:Presence

The endogenous mouse Cd38 gene was replaced by human CD38 gene. While hCD38 mice(Stock No.NM-HU-00113)have been pulled from shelves for some reasons.

Mice

Rag2-KO

Strain Name:C57BL/6Smoc-Rag2em2Smoc
Strain State:Repository Live | Cat. NO.:NM-KO-190429
Validation Data:Presence  |  Publications:2piece

Partial exon 3 of Rag2 gene was deleted to generate Rag2 knockout mice. Deletion of this region will cause frameshift and result in loss of function of mouse Rag2 gene.

Mice

hC1R

Strain Name:C57BL/6Smoc-C1raem1(hC1R)/Smoc
Strain State:Sperm cryopreservation | Cat. NO.:NM-HU-2000075
Validation Data:Presence

The endogenous mouse C1ra gene was replaced by human C1R gene.

Mice

B2m-KO

Strain Name:C57BL/6Smoc-B2mem3Smoc
Strain State:Repository Live | Cat. NO.:NM-KO-18021
Validation Data:Presence  |  Publications:1piece

Exon2-3 of B2m gene were deleted to generate Ifngr1 knockout mice.

Mice

R26-CAG-LSL-hACE2-IRES-tdTomato

Strain Name:C57BL/6Smoc-Gt(ROSA)26Sortm1(SA-FRT-2xpolyA-CAG-FRT-Loxp-stop-loxp-human ACE2-IRES-tdTomato-WPRE-polyA)Smoc
Strain State:Sperm cryopreservation | Cat. NO.:NM-KI-200188
Validation Data:Presence

These mice harbor a SA-FRT-2xpolyA-CAG-FRT-Loxp-stop-loxp-human ACE2-IRES-tdTomato-WPRE-polyAA cassette in the Rosa26 locus generated by homologous recombination.

Mice

hOX40/Cd8a-IRES-Luc-2A-EGFP

Strain Name:C57BL/6Smoc-Tnfrsf4tm1(hTNFRSF4)Cd8atm1(V5-IRES-luc-2A-EGFP)Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-HU-210375

hOX40(NM-HU-00041) was crossed with Cd8a-IRES-Akaluc-2A-EGFP(NM-KI-18030) to generate hOX40/Cd8a-IRES-Akaluc-2A-EGFP mice.

Mice

hAGT

Strain Name:C57BL/6Smoc-Agttm1(hAGT)Smoc
Strain State:Repository Live | Cat. NO.:NM-HU-225082
Validation Data:Presence

The endogenous mouse Agt gene was replaced by human AGT gene.

Mice

Batf3-KO

Strain Name:C57BL/6Smoc-Batf3em1Smoc
Strain State:Repository Live | Cat. NO.:NM-KO-190447

exon 1-2 of Batf3 gene was deleted to generate Batf3 knockout mice.

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