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Models

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Mice

Slc6a4-Cre

Strain Name:C57BL/6Smoc-Slc6a4em1(iCre-pA)Smoc
Strain State:Sperm cryopreservation | Cat. NO.:NM-KI-200115
Validation Data:Presence

A iCre-pA expression cassette was knocked into the Slc6a4 gene start codon site. When crossed with a strain carrying a gene flanked by loxP sites, the flanked gene will be removed in cells expressing Cre. The gene product has been involved in the neurological disorders such as addiction and depression.

Mice

Dicer1-Flox

Strain Name:C57BL/6Smoc-Dicer1em1(flox)Smoc
Strain State:Sperm cryopreservation | Cat. NO.:NM-CKO-200158

These mice carry loxP sites flanking exon 23 of Dicer1 gene. When crossed with a Cre recombinase-expressing strain, this strain is useful in eliminating tissue-specific conditional expression of Dicer1 gene.

Mice

Cd68-2A-zsGreen-2A-Luc

Strain Name:C57BL/6Smoc-Cd68em1(T2A-zsGreen-P2A-Luciferase-WPRE-pA)Smoc
Strain State:Sperm cryopreservation | Cat. NO.:NM-KI-240468

The T2A-zsGreen-P2A-Luciferase-WPRE-pA expression cassette was knocked into the Cd68 gene stop codon site.

Mice

Epor-2A-tdTomato-2A-Cre

Strain Name:C57BL/6Smoc-Eportm(2A-tdTomato-2A-Cre)Smoc
Strain State:Sperm cryopreservation | Cat. NO.:NM-KI-230110
Validation Data:Presence

2A-tdTomato-2A-Cre expression cassette was knocked into the Epor gene stop codon site.

Mice

Acadvl-KO

Strain Name:C57BL/6Smoc-Acadvlem1Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-KO-200908

Exon 3-7 of Acadvl gene was deleted to generate Acadvl knockout mice.

Mice

hPD-1/hSIGLEC15

Strain Name:C57BL/6Smoc-Pdcd1tm1(hPDCD1)Siglec15tm1(hSIGLEC15)Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-HU-2000093

hPD-1(NM-HU-00015) was crossed with hSIGLEC15(NM-HU-190037) to generate hPD-1/hSIGLEC15.

Mice

Lyz2-CreERT2-IRES-EGFP

Strain Name:C57BL/6Smoc-Lyz2em2(CreERT2-IRES-EGFP)Smoc
Strain State:Repository Live | Cat. NO.:NM-KI-18047
Validation Data:Presence

A Kozak-CreERT2-IRES-EGFP expression cassette was knocked into the Lyz2 gene start codon site by homologous recombination.

Mice

hTNFa-Tg

Strain Name:C57BL/6Smoc-Tgtn(hTNFa promoter-hTNFa-pA)Smoc
Strain State:Repository Live | Cat. NO.:NM-TG-200004
Validation Data:Presence

These transgenic mice harbor hTNFa promoter-hTNFa-pA expression cassette.

Mice

R26-CAG-2xKRAB-dCas9-IRES-EGFP

Strain Name:C57BL/6Smoc-Gt(ROSA)26Sorem1(CAG-Loxp-2xKRAB-dCas9-IRES-EGFP)Smoc
Strain State:Repository Live | Cat. NO.:NM-KI-18007
Validation Data:Presence

These mice harbor a CAG-LSL-2xKRAB-dCas9-IRES-EGFP-WPRE-pA conditional expression cassette in mouse Rosa26 loci via homologous recombination. This strain can be used in CRISPR mediated target gene transcriptional inhibition (CRISPRi). The loxp-stop-loxp cassette was deleted.

Mice

hCD3EDG/hTPBG

Strain Name:C57BL/6Smoc-Cd3etm1(hCD3E)Cd3dtm1(hCD3D)Cd3gtm1(hCD3G)Tpbgtm1(hTPBG)Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-HU-220111

hCD3EDG(NM-HU-220120) mice were crossed with hTPBG(NM-HU-200239) mice to generate hCD3EDG/hTPBG mice

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