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Models

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Mice

Lmna-c.C1827T

Strain Name：C57BL/6Smoc-Lmnatm1(G609G)Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-KI-200284
Validation Data：Presence

These mice carry a G609G mutation of Lmna gene.

Mice

hPD-1/hTIGIT/hTIM3

Strain Name：C57BL/6Smoc-Pdcd1tm1(hPDCD1)Tigittm1(hTIGIT) Havcr2tm1(hHAVCR2)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-190029

hPD-1(NM-HU-00015),hTIGIT(NM-HU-00053) were crossed with hTIM3(NM-HU-00054) to generate hPD-1/hTIGIT/hTIM3.

Mice

Fcgr2b-Fcgr3-Fcgr4-KO/hPD-1

Strain Name：C57BL/6Smoc-Fcgr2bem1Fcgr3em1Fcgr4em1Pdcd1em1(hPDCD1)Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-KO-220068

The Fcgr2b-Fcgr3-Fcgr4-KO/hPD-1 mouse model was obtained by deleting all sequences from upstream of Fcgr3 gene to the 3'UTR of Fcgr2b gene in the hPD-1(NM-HU-00015) mouse.

Mice

Cspg4-CreERT2-2A

Strain Name：C57BL/6Smoc-Cspg4em(CreERT2-P2A)1Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-KI-225033
Validation Data：Presence

CreERT2-P2A expression cassette was knocked into the Cspg4 gene .

Mice

Clec4f-IRES-Cre-2A-tdTomato

Strain Name：C57BL/6Smoc-Clec4fem1(IRES-iCre-2A-tdTomato)Smoc
Strain State：Repository Live | Cat. NO.：NM-KI-200069
Validation Data：Presence

A IRES-iCre-2A-tdTomato expression cassette was knocked into the Clec4f gene stop codon site.

Mice

Agr2-2A-CreERT2(2)

Strain Name：C57BL/6Smoc-Agr2em1(2A-CreERT2-WPRE-pA)Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-KI-231956

The 2A-CreERT2-WPRE-pA expression cassette was knocked into the Agr2 gene stop codon site.

Mice

R26-CAG-LSL-hFGFR2-IRES-Luc-2A-EGFP

Strain Name：C57BL/6Smoc-Gt(ROSA)26Sortm1(SA-2xpolyA-CAG-LSL-FGFR2-luciferase-EGFP)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-KI-190007

A SA-2xpolyA-CAG-LSL-FGFR2-IRES-luciferase-2A-EGFP-WPRE-polyA cassette was inserted at the Rosa26 locus. When bred to a strain expressing Cre recombinase under control of various tissue specific promoters, Cre recombination deletes the LSL cassette and allows the expression of the FGFR2 protein.

Mice

Tsc1-Flox

Strain Name：C57BL/6Smoc-Tsc1tm1(flox)Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-CKO-200231

These mice carry loxP sites flanking exon 17-18 of Tsc1 gene. When crossed with a Cre recombinase-expressing strain, this strain is useful in eliminating tissue-specific conditional expression of Tsc1 gene.

Mice

Osr2-IRES-CreERT2

Strain Name：C57BL/6Smoc-Osr2em(IRES-CreERT2-Wpre-pA)Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-KI-215086

IRES-CreERT2-Wpre-pA expression cassette was knocked into the Osr2 gene .

Mice

hPD-1/hVEGFR2

Strain Name：C57BL/6Smoc-Pdcd1tm1(hPDCD1)Kdrtm2(hKDR)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-2000098

hPD-1(NM-HU-00015) was crossed with hKDR(NM-HU-00098) to generate hPD-1/hKDR.

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