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Models

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Mice

hC1S

Strain Name：C57BL/6Smoc-C1s1em1(hC1S)/Smoc
Strain State：Repository Live | Cat. NO.：NM-HU-2000077

The endogenous mouse C1s1 gene was replaced by human C1S gene.

Mice

Ly6g-Cre-2A-tdTomato

Strain Name：C57BL/6Smoc-Ly6gem2(iCre-P2A-tdTomato-polyA)Smoc
Strain State：Repository Live | Cat. NO.：NM-KI-200219

A iCre-P2A-tdTomato-polyA expression cassette was knocked into the Ly6g gene start codon site.

Mice

hCCR4(2)

Strain Name：C57BL/6Smoc-Ccr4tm1(hCCR4)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-215015

The endogenous mice Ccr4 gene was replaced by human CCR4 gene.

Mice

hGLP1R

Strain Name：C57BL/6Smoc-Glp1rem2(hGLP1R)Smoc
Strain State：Repository Live | Cat. NO.：NM-HU-200220

The endogenous mouse Glp1r gene was completely or partially replaced by human hGLP1R gene via CRISPR/Cas9 mediated recombination.

Mice

hAQP4

Strain Name：C57BL/6Smoc-Aqp4em1(hAQP4)/Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-210001

The endogenous mice Aqp4 gene was replaced by human AQP4 gene

Mice

hAPOC3

Strain Name：C57BL/6Smoc-Apoc3em1(hAPOC3)Smoc
Strain State：Repository Live | Cat. NO.：NM-HU-225050

The endogenous mouse Apoc3 gene was replaced by human APOC3 gene.

Mice

hCCL4

Strain Name：C57BL/6Smoc-Ccl4em1(hCCL4)/Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-210013

The endogenous mice Ccl4 gene was replaced by human CCL4 gene

Mice

hCCR8(2)

Strain Name：C57BL/6Smoc-Ccr8em3(hCCR8)/Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-2000054

The endogenous mouse Ccr8 gene was replaced by human CCR8 gene. While hCCR8(Stock No.NM-HU-190053) mice function similarly to hCCR8(2) mice,for more detailed information please contact our technical advisor.

Mice

Acadm-repeat(E8-10)

Strain Name：C57BL/6Smoc-Acadmem1(E8-10 repeat)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-KI-200239

A E8-10 repeat cassette was knocked after exon10 of the Acadm gene.

Mice

Ace2-2A-CreERT2

Strain Name：C57BL/6Smoc-Ace2em2(2A-CreERT2-WPRE-polyA)Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-KI-200187

A 2A-CreERT2-WPRE-polyA expression cassette was knocked into the Ace2 gene stop codon site. Ace2 encodes angiotensin I converting enzyme 2. When crossed with a strain carrying a gene flanked by loxP sites, the flanked gene will be removed in cells expressing Cre. This strain is useful for studying lung injury and kidney disease caused by SARS coronavirus infection.

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