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Models

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Mice

Cd8a-IRES-DTRGFP/Cd8a-IRES-Luc-2A-EGFP

Strain Name：C57BL/6Smoc-Cd8aem2(IRES-DTREGFP)Cd8aem1(V5-IRES-luci-2A-EGFP)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-KI-210399

Cd8a-IRES-DTRGFP(NM-KI-190045) was crossed with Cd8a-IRES-Luc-2A-EGFP(NM-KI-18030) to generate Cd8a-IRES-DTRGFP/Cd8a-IRES-luc-2A-EGFP mice.

Mice

h4-1BBL

Strain Name：C57BL/6Smoc-Tnfsf9tm1(hTNFSF9)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-00048
Validation Data：Presence

The endogenous mouse Tnfsf9 gene was replaced by human TNFSF9 gene.

Mice

Tmem119-2A-tdTomato-2A-DTR

Strain Name：C57BL/6Smoc-Tmem119em1(2A-tdTomato-2A-DTR)Smoc
Strain State：Repository Live | Cat. NO.：NM-KI-210117
Validation Data：Presence

2A-tdTomato-2A-DTR expression cassette was knocked into the Tmem119 gene.

Mice

Adgre1-2A-CreERT2

Strain Name：C57BL/6Smoc-Adgre1em1(2A-CreERT2)Smoc
Strain State：Repository Live | Cat. NO.：NM-KI-190025
Validation Data：Presence

A 2A-CreERT2 expression cassette was knocked into the Adgre1 gene stop codon site.

Mice

Ace2-2A-CreERT2

Strain Name：C57BL/6Smoc-Ace2em2(2A-CreERT2-WPRE-polyA)Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-KI-200187
Validation Data：Presence

A 2A-CreERT2-WPRE-polyA expression cassette was knocked into the Ace2 gene stop codon site. Ace2 encodes angiotensin I converting enzyme 2. When crossed with a strain carrying a gene flanked by loxP sites, the flanked gene will be removed in cells expressing Cre. This strain is useful for studying lung injury and kidney disease caused by SARS coronavirus infection.

Mice

Cdkn2a-Luc-2A-tdTomato-2A-CreERT2(p16-Luc-2A-tdTomato-2A-CreERT2)

Strain Name：C57BL/6Smoc-Cdkn2aem(Luc-tdTomato-CreERT2)Smoc
Strain State：Repository Live | Cat. NO.：NM-KI-18039
Validation Data：Presence  |  Publications：1piece

A Luc-2A-tdTomato-2A-CreERT2-WPRE-pA cassette was fused in-frame with exon2 of p16INK4a transcript such that the exogenous proteins would be translated followed by the first 62aa of Cdkn2a.

Mice

hANGPTL3(4)

Strain Name：C57BL/6Smoc-Angptl3tm1(hANGPTL3)Smoc
Strain State：Repository Live | Cat. NO.：NM-HU-210036
Validation Data：Presence

The endogenous mice Angptl3 gene was replaced by human ANGPTL3 gene. While hANGPTL3(Stock No.NM-HU-200113) have been pulled from shelves for some reasons and hANGPTL3(3)(Stock No.NM-HU-210037) mice function similarly to hANGPTL3(2) mice, for more detailed information please contact our technical advisor.

Mice

Rag2/IL2rg-KO/hCD40

Strain Name：C57BL/6Smoc-Cd40tm1(hCD40)Rag2em1Il2rgem1Smoc
Strain State：Developing | Cat. NO.：NM-HU-2000112

The Rag2 and Il2rg genes of the CD40 humanized mouse were deleted.

Mice

hOCLN

Strain Name：C57BL/6Smoc-Oclntm1(hOCLN)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-190072

The endogenous mouse Ocln gene was replaced by human OCLN gene.

Mice

hCCR2

Strain Name：C57BL/6Smoc-Ccr2tm2(hCCR2)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-18026
Validation Data：Presence

The endogenous mouse Ccr2 gene was replaced by human CCR2 gene.

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