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Mice

R26-CAG-LSL-RSR-tdTomato-2A-DTR

Strain Name：C57BL/6Smoc-Gt(ROSA)26Sorem1(CAG-LSL-RSR-tdTomato-2A-DTR)Smoc
Strain State：Repository Live | Cat. NO.：NM-KI-190086
Validation Data：Presence  |  Publications：2piece

These mice harbor a CAG-LSL-RSR-tdTomato-2A-DTR cassette in the Rosa26 locus generated by homologous recombination.

Mice

hPD-L1

Strain Name：C57BL/6Smoc-Cd274tm1(hPD-L1)Smoc
Strain State：Repository Live | Cat. NO.：NM-HU-00062
Validation Data：Presence  |  Publications：1piece

The endogenous mouse Cd274(also known as PD-L1) gene was replaced by human PD-L1 gene . While hPD-L1(2)(Stock No.NM-HU-190039) mice function similarly to hPD-L1 mice,for more detailed information please contact our technical advisor.

Mice

hACE2

Strain Name：C57BL/6Smoc-Ace2tm3(hACE2-flag-Wpre-pA)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-200218
Validation Data：Presence  |  Publications：1piece

A human ACE2-flag-Wpre-pA expression cassette was knocked into the Ace2 gene start codon site via CRISPR/Cas9 mediated recombination.

Mice

hCD81

Strain Name：C57BL/6Smoc-Cd81tm1(CD81)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-190041

The endogenous mouse Cd81 gene was replaced by human CD81 gene.

Mice

Kras-LSL-G12D

Strain Name：C57BL/6Smoc-Krasem4(LSL-G12D)Smoc
Strain State：Repository Live | Cat. NO.：NM-KI-190003
Validation Data：Presence  |  Publications：2piece

exon2 of Kras were replaced by loxp-stop-loxp and exon2 containing G12D. When crossed with a Cre recombinase-expressing strain, this strain is useful in studies of cancer and development.

Mice

hCD81/hOCLN

Strain Name：C57BL/6Smoc-Cd81tm1(hCD81)Oclntm1(hOCLN)Smoc
Strain State：Repository Live | Cat. NO.：NM-HU-2000107

These mice are obtained through breeding of two single gene humanized mice.

Mice

hDPP4

Strain Name：C57BL/6Smoc-Dpp4tm1(DPP4)Smoc
Strain State：Repository Live | Cat. NO.：NM-HU-190042
Validation Data：Presence  |  Publications：1piece

The endogenous mouse Dpp4 gene was replaced by human DPP4 gene.

Mice

Acta2-CreERT2

Strain Name：C57BL/6Smoc-Acta2em1(CreERT2-Wpre-polyA)Smoc
Strain State：Repository Live | Cat. NO.：NM-KI-200074
Validation Data：Presence

A CreERT2-Wpre-polyA expression cassette was knocked into the Acta2 gene start codon site.

Mice

Ccr2-2A-DreERT2

Strain Name：C57BL/6Smoc-Ccr2em3(2A-DreERT2)Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-KI-200023
Validation Data：Presence  |  Publications：1piece

A 2A-DreERT2 expression cassette was knocked into the Ccr2 gene stop codon site.

Mice

h4-1BB(2)

Strain Name：C57BL/6Smoc-Tnfrsf9tm2(TNFRSF9)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-190077
Validation Data：Presence

The endogenous mouse Tnfrsf9 gene was replaced by human TNFRSF9(4-1BB) gene. While h4-1BB mice(Stock No.NM-HU-00099）have been pulled from shelves for some reasons.

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