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Models

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Mice

Cd19-IRES-DTRGFP

Strain Name:C57BL/6Smoc-Cd19em2(IRES-DTREGFP)Smoc
Strain State:Repository Live | Cat. NO.:NM-KI-190042
Validation Data:Presence

A IRES-DTREGFP expression cassette was knocked into the Cd19 gene stop codon site.

Mice

Adh7-KO

Strain Name:C57BL/6Smoc-Adh7em1Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-KO-201121

Exon 3 of Adh7 gene was deleted to generate Adh7 knockout mice.

Mice

hAppNL-G-F

Strain Name:C57BL/6Smoc-Apptm3(hAppNL-G-F)/Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-HU-2000088
Validation Data:Presence

The endogenous mouse App gene was replaced by human AppNL-G-F.

Mice

hC5AR1/C5AR2

Strain Name:C57BL/6Smoc-C5ar1tm1(hC5AR1)C5ar2tm1(hC5AR2)/Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-HU-2000018
Validation Data:Presence

The endogenous mouse C5ar1 and C5ar2 gene was replaced by human C5AR1 and hC5AR2 gene.

Mice

hGLP1R

Strain Name:C57BL/6Smoc-Glp1rtm2(hGLP1R)Smoc
Strain State:Repository Live | Cat. NO.:NM-HU-200220
Validation Data:Presence  |  Publications:1piece

The endogenous mouse Glp1r gene was completely or partially replaced by human hGLP1R gene via CRISPR/Cas9 mediated recombination.

Mice

Ly6g-2A-CreERT2

Strain Name:C57BL/6Smoc-Ly6gem3(2A-CreERT2)Smoc
Strain State:Repository Live | Cat. NO.:NM-KI-200218
Validation Data:Presence

A 2A-CreERT2 expression cassette was knocked into the Ly6g gene stop codon region.

Mice

Anxa10-2A-CreERT2

Strain Name:C57BL/6Smoc-Anxa10em1(2A-CreERT2-Wpre-pA)Smoc
Strain State:Repository Live | Cat. NO.:NM-KI-200312
Validation Data:Presence

2A-CreERT2-Wpre-pA expression cassette was knocked into the Anxa10 gene stop codon site.

Mice

Epcam-2A-CreERT2

Strain Name:C57BL/6Smoc-Epcamem1(2A-CreERT2)Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-KI-00084
Validation Data:Presence

An 2A-CreERT2 co-expression cassette is inserted before 3'UTR region of Epcam gene .

Mice

Axin2-CreERT2

Strain Name:C57BL/6Smoc-Axin2em1(CreERT2-pA)Smoc
Strain State:Sperm cryopreservation | Cat. NO.:NM-KI-200109
Validation Data:Presence

A CreERT2-pA expression cassette was knocked into the Axin2 gene start codon site. As Axin2 is an intracellular protein, it is essential for identifying a surface marker for stem cell purification. When these Axin2-CreERT2 mice are bred with mice containing a loxP-flanked sequence of interest, tamoxifen-inducible, Cre-mediated recombination will result in deletion of the flanked sequences in Axin2 expressing cells.

Mice

hPD-1/hPD-L1/hOX40

Strain Name:C57BL/6Smoc-Tnfrsf4tm3(hTNFRSF4)Pdcd1tm1(hPDCD1)Cd274tm1(hPD-L1)Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-HU-00122

hPD-1(NM-HU-00015),hPD-L1(NM-HU-00062) were crossed with hOX40(NM-HU-00041) to generate hPD-1/hPD-L1/hOX40.

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