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Models

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Mice

Rag2/IL2rg-KO/hVEGFR2

Strain Name：C57BL/6Smoc-Il2rgem1Kdrtm2(hKDR)Rag2em1Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-220087

IL2rg-KO (NM-KO-210098) mice were crossed with Rag2-KO/hKDR (NM-HU-200280) mice to generate Rag2/IL2rg-KO/hKDR mouse models.

Mice

Epcam-2A-CreERT2

Strain Name：C57BL/6Smoc-Epcamem1(2A-CreERT2)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-KI-00084

An 2A-CreERT2 co-expression cassette is inserted before 3'UTR region of Epcam gene .

Mice

Zbtb46-2A-CreERT2

Strain Name：C57BL/6Smoc-Zbtb46em1(2A-CreERT2-WPRE-pA)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-KI-18021

A 2A-CreERT2-WPRE-pA coexpression cassette is inserted befor the stop codon of mouse Zbtb46 gene via homologous recombination to establish a tamoxifen inducible Zbtb46-CreERT2 tool stain. This strain can be used to knockout target gene in Zbtb46+ cells after tamoxifen treatment when crossed with mice which carry loxp sites flanking target gene.

Mice

hCTLA-4

Strain Name：C57BL/6Smoc-Ctla4em1(hCTLA4) Smoc
Strain State：Repository Live | Cat. NO.：NM-HU-00014

The endogenous mouse Ctal4 gene was replaced by human CTLA4 gene. While hCTLA4(2)(Stock No.NM-HU-190038) mice function similarly to hCTLA4 mice,for more detailed information please contact our technical advisor.

Mice

Lgr5-EGFP-IRES-CreERT2

Strain Name：C57BL/6Smoc-Lgr5em1(EGFP-IRES-creERT2-WPRE-polyA)Smoc
Strain State：Repository Live | Cat. NO.：NM-KI-200154

A EGFP-IRES-creERT2-WPRE-polyA expression cassette was knocked into the Lgr5 gene start codon site.

Mice

hVISTA

Strain Name：C57BL/6Smoc-Vsirem1(hVSIR)/Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-00118

The exon 2-3 of endogenous mouse Vsir gene was replaced by the exon 2-3 of human VSIR(VISTA) gene.

Mice

hCSF1

Strain Name：C57BL/6Smoc-Csf1tm2(CSF1)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-190043

The endogenous mouse Csf1 gene was replaced by human CSF1 gene.

Mice

Fcgr1-KO

Strain Name：C57BL/6Smoc-Fcgr1em1Smoc
Strain State：Repository Live | Cat. NO.：NM-KO-18033

The Fcgr1 knockout mouse model was obtained by knocking out all coding regions of mouse Fcgr1 gene.

Mice

Procr-CreERT2-2A-tdTomato

Strain Name：C57BL/6Smoc-Procrem5(CreERT2-P2A-tdtomato-Wpre-pA)Smoc
Strain State：Repository Live | Cat. NO.：NM-KI-200227

A CreERT2-P2A-tdtomato-Wpre-pA expression cassette was knocked into the Procr gene start codon site.

Mice

hSTING

Strain Name：C57BL/6Smoc-Tmem173tm2(hTMEM173)Smoc
Strain State：Repository Live | Cat. NO.：NM-HU-190036

The endogenous mouse Tmem173 gene was replaced by human TMEM173 gene.

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