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Mice

BALB/c Nude

Strain Name：BALB/cAnSmoc-Foxn1nu/Smoc
Strain State：Repository Live | Cat. NO.：SM-014
Validation Data：有

This strain carries a Foxn1nu mutation on the BALB/c background which will lead to T cell deletion. At the same time, the response to thymus-dependent antigens is limited, resulting in impaired B cell function while NK cells, macrophages, and antigen-presenting cells function normally. The complement activity is normal as well. Hair dysplasia causes aberrant hair growth in which the majority of the hair cannot protrude from the surface, resulting in a naked mouse phenotype.

Mice

R26-CAG-LSL-hCD2*C truncated

Strain Name：C57BL/6Smoc-Gt(ROSA)26Sorem1(CAG-LSL-hCD2 C truncated-WPRE-polyA)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-KI-200321
Validation Data：无

A CAG-LSL-hCD2 C truncated-WPRE-polyA expression cassette was knocked into the R26 locus.

Mice

BALB/c

Strain Name：BALB/cAnSmoc
Strain State：Repository Live | Cat. NO.：SM-003
Validation Data：无

BALB/c is one of the most widely used inbred lines in biomedical research, especially in immunology and infectious disease research. The incidence of breast tumors is about 10% to 20%. There is a certain number of ovarian, adrenal, pulmonary tumors, and leukemia that occurs. Lung cancer occurs in 26% of female mice and 29% of male mice. The incidence of leukemia is 12% in females and 10% in males. Blood pressure was the highest compared to other inbred mice and had spontaneous hypertension.

Mice

R26-CAG-LSL-hMET-IRES-Luc-2A-tdTomato

Strain Name：C57BL/6Smoc-Gt(ROSA)26Sorem1(CAG-LSL-c-MET-IRES-luciferase-2A-tdTomato)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-KI-18052
Validation Data：无

A SA-2xpolyA-CAG-Loxp-Stop-Loxp-human cMET-IRES-luciferase-2A-tdTomato-wpre-polyA cassette was knocked into the mouse Rosa26 locus . This strain of mice can be mated with mice expressing Cre recombinase so that human C-MET could be expressed after exposure to Cre recombinase.

Mice

hMUC1-c.462insC

Strain Name：C57BL/6Smoc-Muc1em(hMUC1-c.462insC)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-220410
Validation Data：有

The endogenous mouse Muc1 gene was replaced by human hMUC1-c.462insC gene.

Mice

Spink1-c.197+2t>c

Strain Name：C57BL/6Smoc-Spink1em1c.197+2t>cSmoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-KI-232249
Validation Data：无

These strains carry a c.197+2t>c mutation of Spink1 gene.

Mice

Scn1a-c.473+5G>A

Strain Name：C57BL/6Smoc-Scn1aem1(c.473+5G>A)Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-KI-210417
Validation Data：无

These mice carry a c.473+5G>A mutation of Scn1a gene.

Mice

Fos-CreERT2

Strain Name：C57BL/6Smoc-Fosem1(CreERT2-SV40-pA)Smoc
Strain State：Repository Live | Cat. NO.：NM-KI-200110
Validation Data：有

A CreERT2 expression cassette was knocked into the Fos gene start codon site.

Mice

Sftpc-IRES-CreERT2

Strain Name：C57BL/6Smoc-Sftpcem(IRES-CreERT2)Smoc
Strain State：Repository Live | Cat. NO.：NM-KI-18020
Validation Data：有

An IRES-CreERT2 co-expression cassette is inserted into 3'UTR region of Sftpc gene via homologous recombination to establish a tamoxifen inducible Sftpc-CreERT2 tool stain. *This strain CreERT2 has leakage (see validation data for details), please select according to the purpose of the study。

Mice

Fgfr1-2A-CreERT2(2)

Strain Name：C57BL/6Smoc-Fgfr1em2(2A-CreERT2-WPRE-pA)Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-KI-225051
Validation Data：无

2A-CreERT2-WPRE-pA expression cassette was knocked into the Fgfr1 gene .

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