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Models

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Mice

Cd8a-2A-CreERT2

Strain Name：C57BL/6Smoc-Cd8aem1(2A-CreERT2)Smoc
Strain State：Repository Live | Cat. NO.：NM-KI-234690
Validation Data：Presence

The 2A-CreERT2 expression cassette was knocked into the Cd8a gene stop codon site.

Mice

Cblif-2A-Dre(2)

Strain Name：C57BL/6Smoc-Cblifem1(2A-Dre-WPRE-pA)Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-KI-231957
Validation Data：Absence

The 2A-Dre-WPRE-pA expression cassette was knocked into the Cblif gene stop codon site.

Mice

Cd45.1(BALB/c)

Strain Name：BALB/cAnSmoc-Ptprcem2(K302E)Smoc
Strain State：Repository Live | Cat. NO.：NM-KI-210227
Validation Data：Presence

These mice carry a K302E mutation of Ptprc gene.

Mice

Cd274-KO(2)

Strain Name：C57BL/6Smoc-Cd274em2Smoc
Strain State：Repository Live | Cat. NO.：NM-KO-18044
Validation Data：Presence

Cd274 gene is also called B7-H1, Pdcd1lg1 or PD-L1. The PD-L1-KO(2) mouse model was obtained by deleting the Exon 3-5 region of mouse Cd274 gene. While PD-L1-KO(Stock No.NM-KO-00104) mice have been pulled from shelves for some reasons.

Mice

Cd276-KO

Strain Name：C57BL/6Smoc-Cd276em2Smoc
Strain State：Repository Live | Cat. NO.：NM-KO-18039
Validation Data：Presence

The Cd276 knockout mouse model was obtained by knocking out the exon 3-4 region of mouse Cd276 gene.

Mice

Cx3cr1-DreERT2

Strain Name：C57BL/6Smoc-Cx3cr1em(Kozak-DreERT2-WPRE-PA)Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-KI-220233
Validation Data：Absence

Kozak-DreERT2-WPRE-PA expression cassette was knocked into the Cx3cr1 gene start codon site.

Mice

Csf2-KO

Strain Name：C57BL/6Smoc-Csf2em2Smoc
Strain State：Repository Live | Cat. NO.：NM-KO-190532
Validation Data：Absence

Exon 1-3 of Csf2 gene was deleted to generate Csf2 knockout mice. Homozygotes for targeted null mutations exhibit lung abnormalities with lymphocytic infiltration and accumulation of surfactant lipids. Litter sizes from homozygous breeding pairs are smaller at weaning due to perinatal mortality (Note from MGI).

Mice

Clec9a-2A-CreERT2

Strain Name：C57BL/6Smoc-Clec9aem2(2A-CreERT2-WPRE-polyA)Smoc
Strain State：Repository Live | Cat. NO.：NM-KI-200022
Validation Data：Absence

A 2A-CreERT2-WPRE-polyA expression cassette was knocked into the Clec9a gene stop codon site.

Mice

Crhr1-IRES-Cre

Strain Name：C57BL/6Smoc-Crhr1em1(IRES-Cre)Smoc
Strain State：Repository Live | Cat. NO.：NM-KI-233206
Validation Data：Absence

The IRES-Cre expression cassette was knocked into the Crhr1 gene stop codon site.

Mice

Ccl4-KO

Strain Name：C57BL/6Smoc-Ccl4em1Smoc
Strain State：Repository Live | Cat. NO.：NM-KO-190016
Validation Data：Absence

This Ccl4 knockout mouse model was generated by knocking out the exon 2 region of the Ccl4 .

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