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Models

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Mice

Ifi206-Flox

Strain Name：C57BL/6Smoc-Ifi206em1(flox)Smoc
Strain State：Developing | Cat. NO.：TBD
Validation Data：Absence

These mice carry loxP sites flanking target exons of Ifi206 gene. When crossed with a Cre recombinase-expressing strain, this strain is useful in eliminating tissue-specific conditional expression of Ifi206 gene.

Mice

Ifi206-KO

Strain Name：C57BL/6Smoc-Ifi206em1Smoc
Strain State：Developing | Cat. NO.：TBD
Validation Data：Absence

Exon 3 of Ifi206 gene was deleted to generate Ifi206 knockout mice.

Mice

Pck1-Flox

Strain Name：C57BL/6Smoc-Pck1em(flox)/Smoc
Strain State：Repository Live | Cat. NO.：NM-CKO-220267
Validation Data：Absence

These mice carry loxP sites flanking exon4-5 of Pck1 When crossed with a Cre recombinase-expressing strain, this strain is useful in eliminating tissue-specific conditional expression of Pck1 gene.

Mice

Mbl2-KO

Strain Name：C57BL/6Smoc-Mbl2em1Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-KO-205437
Validation Data：Absence

Exon 4-6 of Mbl2 gene was deleted to generate Mbl2 knockout mice.

Mice

Mbl2-Flox

Strain Name：C57BL/6Smoc-Mbl2em1(flox)Smoc
Strain State：Developing | Cat. NO.：TBD
Validation Data：Absence

These mice carry loxP sites flanking target exons of Mbl2 gene. When crossed with a Cre recombinase-expressing strain, this strain is useful in eliminating tissue-specific conditional expression of Mbl2 gene.

Mice

Pate6-Flox

Strain Name：C57BL/6Smoc-Pate6em1(flox)Smoc
Strain State：Developing | Cat. NO.：TBD
Validation Data：Absence

These mice carry loxP sites flanking target exons of Pate6 gene. When crossed with a Cre recombinase-expressing strain, this strain is useful in eliminating tissue-specific conditional expression of Pate6 gene.

Mice

Pate5-Flox

Strain Name：C57BL/6Smoc-Pate5em1(flox)Smoc
Strain State：Developing | Cat. NO.：TBD
Validation Data：Absence

These mice carry loxP sites flanking target exons of Pate5 gene. When crossed with a Cre recombinase-expressing strain, this strain is useful in eliminating tissue-specific conditional expression of Pate5 gene.

Mice

Pate5-KO

Strain Name：C57BL/6Smoc-Pate5em1Smoc
Strain State：Developing | Cat. NO.：TBD
Validation Data：Absence

Exon 2-3 of Pate5 gene was deleted to generate Pate5 knockout mice.

Mice

Pate6-KO

Strain Name：C57BL/6Smoc-Pate6em1Smoc
Strain State：Developing | Cat. NO.：TBD
Validation Data：Absence

Exon 3 of Pate6 gene was deleted to generate Pate6 knockout mice.

Mice

NMG

Strain Name：NOD.Cg-PrkdcscidIl2rgem1Smoc
Strain State：Repository Live | Cat. NO.：NM-NSG-001
Validation Data：Presence

Prkdc and Il2rg genes were both knocked-out in NOD mice. Lacking mature T, B and NK cells; Low immune rejection against human cells and tissues; Good tumorigenicity so that a small number of cells can form tumors; Significant improvement in the survival of transplanted human cells and tissues; Suitable for the transplantation of human hematopoietic stem cells and the preparation of humanized mouse models; Suitable as the carrier mice for the transplantation of heterologous cells and tissues.

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