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Models

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Mice

hCD19/hCD3EDG/hCD28(BALB/c)

Strain Name：BALB/cAnSmoc-Cd19em(hCD19)Cd3etm1(hCD3E)Cd3dtm1(hCD3D)Cd3gtm1(hCD3G)Cd28em(hCD28)Smoc
Strain State：Repository Live | Cat. NO.：NM-XA-251980
Validation Data：无

The hCD19/hCD3EDG(BALB/c) (NM-XA-240066) was crossed with hCD28(BALB/c,3)(NM-HU-220509) to generate hCD19/hCD3EDG(BALB/c)/hCD28(BALB/c,3) mice.

Mice

hPD-1/hPD-L1(BALB/c)

Strain Name：BALB/cAnSmoc-Pdcd1em(hPDCD1)Cd274em(hPD-L1)/Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-220142
Validation Data：无

hPD-1(BALB/c)(NM-HU-190079) mice were crossed with hPD-L1(BALB/c ) (NM-HU-220028) mice to generate hPD-1/ hPD-L1(BALB/c) mice.

Mice

Rag2/Il2rg-KO/hSIRPA(BALB/c,2)

Strain Name：BALB/cAnSmoc-Sirpatm(hSIRPA)Rag2em1IL2rgem1Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-KO-234081
Validation Data：无

On the basis of strain hSIRPA(BALB/c,2), Rag2 and Il2rg gene exon3 and Il2rg gene exon2 were knocked out to establish Rag2 and IL2RG gene knockout mouse models in hSIRPA(BALB/c,2) background.

Mice

Rag2/IL2rg/Flt3-KO(BALB/c)

Strain Name：BALB/cAnSmoc-Rag2em1IL2rgem1Flt3em1Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-KO-234080
Validation Data：有

In the background of Rag2/IL2rg-KO (BALB/c)(NM-KO-210231), the exon3 of Flt3 gene was knocked out to establish Rag2, IL2rg and Flt3 gene knockout mouse models.

Mice

hCD3EDG/Tnfrsf23-2A-TNFRSF10C(BALB/c)

Strain Name：BALB/cAnSmoc-Cd3etm1(hCD3E)Cd3dtm1(hCD3D)Cd3gtm1(hCD3G)Tnfrsf23em1(2A-TNFRSF10C-WPRE-pA)Smoc
Strain State：Developing | Cat. NO.：NM-KI-251881
Validation Data：无

Based on the hCD3EDG(BALB/c) NM-HU-220122 strain, the 2A-TNFRSF10C-WPRE-pA expression cassette was knocked into the Tnfrsf23 gene stop codon site.

Mice

Ighm/Ighd-KO/hSIRPA/hCD47(BALB/c)

Strain Name：BALB/cAnSmoc-Ighmem1Ighdem1Sirpatm4(hSIRPA)Cd47em1(hCD47)/Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-KO-232262
Validation Data：无

The Ighm/Ighd-KO(BALB/c)(NM-KO-210095) was crossed with hSIRPA/hCD47(BALB/c)(NM-HU-210020) to generate Ighm/Ighd-KO(BALB/c)/hSIRPA/hCD47(BALB/c) mice.

Mice

hPD-1/hPD-L1/hCD47/hSIRPA(BALB/c)

Strain Name：BALB/cAnSmoc-Pdcd1em(hPDCD1)Cd274em(hPD-L1)Sirpatm4(hSIRPA)Cd47em1(hCD47)/Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-220143
Validation Data：无

hSIRPA/hCD47(BALB/c)(NM-HU-210020) mice was crossed with hPD-1/ hPD-L1(BALB/c)(NM-HU-220142) mice to generate hPD-1/hPD-L1/hCD47/hSIRPA(BALB/c) mice.

Mice

Igkj-KO/Ighj-KO/Igl-KO(BALB/c)

Strain Name：BALB/cAnSmoc-Igkjem4Ighjem4Iglem4Smoc
Strain State：Repository Live | Cat. NO.：NM-XA-252094
Validation Data：无

The Igkj-KO(BALB/c)/Ighj-KO(BALB/c) (NM-XA-252093) was crossed with Igl-KO(BALB/c)(NM-KO-200583) to generate Igkj-KO(BALB/c)/Ighj-KO(BALB/c)/Igl-KO(BALB/c) mice.

Mice

Lepr-G/T(Intron17)(BALB/c)

Strain Name：BALB/cAnSmoc-Leprem(G/T)Smoc
Strain State：Developing | Cat. NO.：NM-KI-230478
Validation Data：无

G/T was knocked into exon19 of the Lepr gene(c.109052 G>T).

Mice

hCEACAM1(2)

Strain Name：C57BL/6Smoc-Ceacam1em(hCEACAM1)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-220523
Validation Data：无

The endogenous mouse Ceacam1 gene was replaced by human CEACAM1 gene.

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