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Literature

FLI1 promotes IFN-γ-induced kynurenine production to impair anti-tumor immunity

Model Organisms：小鼠 Product & Service：- Research field：

Published date：2024-05-30 | References：Nature Communications

Literature

Identification of mundoserone by zebrafish in vivo screening as a natural product with anti-angiogenic activity

Model Organisms：Rat Product & Service：- Research field：Antiangiogenesis

Published date：2018-09-17 | References：Exp Ther Med

Literature

Integrated multi-omics reveal gut microbiota-mediated bile acid metabolism alteration regulating immunotherapy...

Model Organisms：小鼠 Product & Service：- Research field：

Published date：2024-02-05 | References：Gut Microbes

Literature

The BCL-2 inhibitor APG-2575 resets tumor-associated macrophages toward the M1 phenotype, promoting a favorable...

Model Organisms：小鼠 Product & Service：huHSC-(M-NSG) Research field：The therapeutic mechanism of immunotherapy for non-small cell lung cancer

Published date：2023-12-07 | References：Cellular & Molecular Immunology

Literature

Transcriptional analysis of immune-related genes in dendritic cells from hepatitis B surface antigen (HBsAg)-positive...

Model Organisms：小鼠 Product & Service：HBV-Tg Research field：hepatitis B

Published date：2011-01-01 | References：Journal of Medical Virology

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SMOC Launched U-HuDTMbase®, Inclusive Resource Library of Innovative Therapeutic Target-Humanized Mouse Models, to Accelerate Novel Drug Discovery

U-HuDTMbase® is composed of more than 600 therapeutic target-humanized mouse models, including multiple background strains, and has covered almost all commonly studied areas, such as oncology, metabolism, immunity, inflammation and more.

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Cancer Model

research on cancer cancer model mouse models of cancer

The laboratory mouse is widely considered as a valid and affordable model organism for studying human disease. Mouse models of cancer not only enable researchers to understand the genetic basis of tumor development in complicated and dynamic physiological systems, but also serve as irreplaceable tools for developing and testing new therapies.  Shanghai Model Organisms Center offers a variety of mouse models of cancer to meet the needs of both academic and industry partners.

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