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R26-CAG-loxp-tdTomato-loxp2272-Tag-IRES-EGFP-2A-Luc-loxp-loxp2272/Alb-Cre-Tg

Strain Name：R26-CAG-loxp-tdTomato-loxp2272-Tag-IRES-EGFP-2A-Luc-loxp-loxp2272/Alb-Cre-Tg
Strain State ： Construction |  Cat. NO.：NM-YD14

Derived from R26-CAG-loxp-tdTomato-loxp2272-Tag-IRES-EGFP-2A-Luc-loxp-loxp2272/Alb-Cre-Tg mice spontaneous liver cancer model

Manganese transporter Slc39a14 deficiency revealed its key role in maintaining manganese homeostasis in mice

Model Organisms：小鼠 Product & Service：Slc39a14 Research field：Liver

跨膜金属转运蛋白家族 Alb-cre 肝脏Cre

Methyltransferase SETD2-Mediated Methylation of STAT1 Is Critical for Interferon Antiviral Activity

Model Organisms：小鼠 Product & Service：Setd2 Research field：Hepatitis B

甲基转移酶 乙型肝炎病毒 HBV Alb-cre 肝脏Cre 抗病毒免疫

GEMM-Derived Allografts

Blood Analysis

Mouse serum mouse serum albumin

At Shanghai Model Organisms Center, we use an automatic biochemical analyzer to measure a specific chemical composition of serum according to the principle of photoelectric colorimetry. This can be used to assess liver and kidney functions or measure blood sugar, blood lipids, and electrolytes.

Fibrosis

liver fibrosis model

The mouse liver fibrosis model can be generated by surgery or drug induction, which can be used to study the role of genes and proteins in the development of liver fibrosis, to explore the mechanisms underlying liver fibrosis, and to carry out drug efficacy evaluations.

Mouse models for cancer research

Tumor bearing Mouse DEN model PDX model CDX model

Shanghai Model Organisms Center provides multiple types of tumor-bearing mouse models for cancer research and drug efficacy testing, including cell line-derived xenograft model (CDX) and patient-derived xenograft model (PDX). While PDX models better reflect the heterogeneity and diversity of human cancers, CDX models allow researchers to advance their pre-clinical drug development in a cost- and time-efficient manner.