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Models

About 125 results
Mice

Lrg1-KO

Strain Name：C57BL/6Smoc-Lrg1em1Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-KO-200340

Exon 2 of Lrg1 gene was deleted to generate Lrg1 knockout mice.

Mice

Tbx15-Flox

Strain Name：C57BL/6Smoc-Tbx15tm1Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-CKO-00141

These Tbx15 flox mice possess loxP sites flanking exons 2. When crossed with a Cre recombinase-expressing strain, this strain is useful in eliminating tissue-specific conditional expression of the gene.

Mice

hGLP1R/5xFAD

Strain Name：C57BL/6Smoc-Tg(APPSwFlLon,PSEN1*M146L*L286V)Tfrctm1(hGLP1R)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NMX-HU-234836

The hTFRC(NM-HU-215059) was crossed with 5xFAD to generate hTFRC/5xFAD mice.

Mice

hTREM2/5xFAD

Strain Name：C57BL/6Smoc-Trem2em4(hTrem2)Tg(APPSwFlLon, PSEN1M146LL286V)6799Vas/Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NMX-HU-232494

The hTREM2(NM-HU-2000083) was crossed with 5xFAD to generate hTREM2/5xFAD mice.

Mice

hTFR1/5xFAD

Strain Name：C57BL/6Smoc-Tfrctm1(hTFR1)Tg(APPSwFlLon,PSEN1*M146L*L286V)6799VasSmoc
Strain State：Repository Live | Cat. NO.：NMX-HU-234838

The hTFR1(NM-HU-215059) was crossed with 5xFAD to generate hTFR1/5xFAD mice.

Mice

hIL13/hIL4/hIL4R

Strain Name：C57BL/6Smoc-Il4tm3(hIL4)Il4ratm1(hIL4R)Il13tm3(hIL13)Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-HU-251863

Based on the hIL4/hIL4R(NM-HU-2000106) strain, the endogenous mouse Il13 gene was replaced by human IL13 gene.

Mice

hCD3EDG/hTNFRSF10C-Tg(BALB/c)

Strain Name：BALB/cAnSmoc-Cd3etm1(hCD3E)Cd3dtm1(hCD3D)Cd3gtm1(hCD3G)Tgtn(hTNFRSF10C)1Smoc
Strain State：Repository Live | Cat. NO.：NM-TG-251880

Based on the hCD3EDG(BALB/c) NM-HU-220122 strain, these transgenic mice harbor hTNFRSF10C expression cassettes.

Mice

hCD3EDG/hCXCR5

Strain Name：C57BL/6Smoc-Cd3etm1(hCD3E)Cd3dtm1(hCD3D)Cd3gtm1(hCD3G)Cxcr5tm1(hCXCR5)/Smoc
Strain State：Repository Live | Cat. NO.：NM-HU-252995

The customer requests that this strain be constructed based on the existing mouse NM-HU-220120 (hCD3EDG) of the company.The endogenous mouse Cxcr5 gene was replaced by human CXCR5 gene.

Mice

Gpr89/Prkab2-KO

Strain Name：C57BL/6Smoc-Gpr89em1Prkab2em1Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-KO-18055

The sgRNAs were designed targeting Gpr89 intron11 and Prkab2 intron7 resulting in a sequence deletion of approximately 790 Kb between the Gpr89 gene and the Prkab2 gene.

Mice

Dgcr2/Hira-KO

Strain Name：C57BL/6Smoc-Dgcr2em1Hiraem1Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-KO-18060

the sgRNAs were designed targeting Dgcr2 intron9 and Hira intron24 resulting in a sequence deletion of approximately 0.11 mb between the Dgcr2 gene and the Hira gene.

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