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Harnessing the Power of the Cre-loxP System: Benefits, Challenges, and Applications

This webinar will introduce the Cre-loxP system, a powerful genetic tool that has revolutionized biological research by allowing for conditional gene knockout, knockdown, and overexpression. We will cover the history of the genetic recombination systems, discuss how they enable precise control of gene expression in specific cell types or at specific developmental stages, and present GenoBioTX’s genetically modified models utilizing this method.

SMOC Launched U-HuDTMbase®, Inclusive Resource Library of Innovative Therapeutic Target-Humanized Mouse Models, to Accelerate Novel Drug Discovery

U-HuDTMbase® is composed of more than 600 therapeutic target-humanized mouse models, including multiple background strains, and has covered almost all commonly studied areas, such as oncology, metabolism, immunity, inflammation and more.

Mouse Models Expedite the Elucidation of AD Pathogenesis

ADC Antibody Development

Research on Diseases

genetics diseases studies diseases research diseases

Shanghai Model Organisms provides a professional R&D platform for genetically-engineered mouse, zebrafish and nematode models, a service platform for phenotyping, and a rich repository of disease mouse models to support your studies on disease genetics, pathogenesis, drug treatments, and more.

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As a biotechnology company specializing in animal model R&D, rearing and breeding, as well as analysis and testing, GenoBioTX is dedicated to providing our clients with comprehensive, convenient and professional animal model services.

Liver Cancer PDX Model

PDX PDX models Patient-derived Xenografts

Patient-derived Xenografts (PDX) are advanced preclinical oncology models for drug development. It offers a far better alternative for preclinical drug evaluation as compared to the conventional cell line-derived xenograft model.

Animal Health

Animal Health Care

Shanghai Model Organisms Center (SMOC) provides you with model mice that have been raised under specific pathogen-free (SPF) barriers. Since obtaining AAALAC-accreditation in 2012, Shanghai Model Organisms Center Co., Ltd. has adhered to the standards outlined in the Guide for the Care and Use of Laboratory Animals (Guide). With an experienced team of veterinarians and researchers, advanced equipment, mature testing technologies and strict quality management system, SMOC guarantees consistent quality and is an ideal choice for your project.

Health Report

animal health report

Shanghai Model Organisms Center (SMOC) provides you with model mice that have been raised under specific pathogen-free (SPF) barriers. Since obtaining AAALAC-accreditation in 2012, Shanghai Model Organisms Center Co., Ltd. has adhered to the standards outlined in the Guide for the Care and Use of Laboratory Animals (Guide). You can download the monthly mice health report here.

Mouse models for cancer research

Tumor bearing Mouse DEN model PDX model CDX model

Shanghai Model Organisms Center provides multiple types of tumor-bearing mouse models for cancer research and drug efficacy testing, including cell line-derived xenograft model (CDX) and patient-derived xenograft model (PDX). While PDX models better reflect the heterogeneity and diversity of human cancers, CDX models allow researchers to advance their pre-clinical drug development in a cost- and time-efficient manner.