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Models

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Mice

hANGPTL3(4)

Strain Name：C57BL/6Smoc-Angptl3tm1(hANGPTL3)Smoc
Strain State：Repository Live | Cat. NO.：NM-HU-210036
Validation Data：Presence

The endogenous mice Angptl3 gene was replaced by human ANGPTL3 gene. While hANGPTL3(Stock No.NM-HU-200113) have been pulled from shelves for some reasons and hANGPTL3(3)(Stock No.NM-HU-210037) mice function similarly to hANGPTL3(2) mice, for more detailed information please contact our technical advisor.

Mice

hANGPTL3(3)

Strain Name：C57BL/6Smoc-Angptl3tm2(hANGPTL3)Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-HU-210037
Validation Data：Presence

The endogenous mice Angptl3 gene was replaced by human ANGPTL3 gene. While hANGPTL3(Stock No.NM-HU-200113) have been pulled from shelves for some reasons and hANGPTL3(4)(Stock No.NM-HU-210036) mice function similarly to hANGPTL3(3) mice, for more detailed information please contact our technical advisor.

Mice

hOX40(2)

Strain Name：C57BL/6Smoc-Tnfrsf4tm3(hTNFRSF4) Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-00078
Validation Data：Presence

The exon1-5 and partial exon6 of endogenous mouse Tnfrsf4(Ox40) gene was replaced by the corresponding region of human TNFRSF4(OX40) gene. While hOX40(Stock No.NM-HU-00041) mice function similarly to hOX40(2) mice,for more detailed information please contact our technical advisor.

Mice

R26-CAG-EGFP(2)

Strain Name：C57BL/6Smoc-Gt(ROSA)26Sorem1(CAG-EGFP-WPRE-polyA)Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-KI-190089

These mice harbor a CAG-EGFP-WPRE-polyA cassette in the Rosa26 locus.1 generated by homologous recombination. While R26-CAG-EGFP(Stock No.NM-KI-190088) and R26-CAG-EGFP(3)(Stock No.NM-KI-190090) function similarly to R26-CAG-EGFP(2) mice,for more detailed information please contact our technical advisor.

Mice

R26-CAG-EGFP(3)

Strain Name：C57BL/6Smoc-Gt(ROSA)26Sorem2(CAG-EGFP-WPRE-polyA)Smoc
Strain State：Repository Live | Cat. NO.：NM-KI-190090
Validation Data：Presence  |  Publications：1piece

These mice harbor a CAG-EGFP-WPRE-polyA cassette in the Rosa26 locus.2 generated by homologous recombination. While R26-CAG-EGFP(Stock No.NM-KI-190088) and R26-CAG-EGFP(2)(Stock No.NM-KI-190089) function similarly to R26-CAG-EGFP(3) mice,for more detailed information please contact our technical advisor.

Mice

Pah-KO

Strain Name：C57BL/6Smoc-Pahem1Smoc
Strain State：Repository Live | Cat. NO.：NM-KO-2110565
Validation Data：Presence

Exon 2-5 of pah gene was deleted to generate pah knockout mice. The homozygous (HO) mice have a certain mortality rate (approximately 15%). Heterozygous (HE) mice are recommended for colony establishment. If you need to purchase homozygous (HO) mice directly for experiments, it is recommended to purchase an additional 15%-20% to avoid mouse death affecting subsequent experiments.

Mice

hFCRN

Strain Name：C57BL/6Smoc-Gt(ROSA)26Sortm1(CAG-hFcRn)Fcgrtem1Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-00109
Validation Data：Presence  |  Publications：1piece

This FcRn humanized strain is established by mating endogenous mouse Fcgrt gene Knockout mice with R26-hFcRn(FCGRT) Knock-in mice. These FcRn humanized mouse models can be useful for evalueting the efficacy of potential immunotherapy drug combinations. While hFCRN(2)(Stock No.NM-HU-190070) and hFCRN(3)(Stock No.NM-HU-2000032）mice function similarly to hFCRN mice,for more detailed information please contact our technical advisor.

Mice

Chgb-KO

Strain Name：C57BL/6Smoc-Chgbem1Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-KO-190935

Exon 2 of Chgb gene was deleted to generate Chgb knockout mice.

Mice

Clec4b2-KO

Strain Name：C57BL/6Smoc-Clec4b2em1Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-KO-190781

Exon 4 of Clec4b2 gene was deleted to generate Clec4b2 knockout mice.

Mice

Taok3-KO

Strain Name：C57BL/6Smoc-Taok3em1Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-KO-191048

Exon 6-7 of Taok3 gene was deleted to generate Taok3 knockout mice.

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