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Models

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Mice

hVEGFA

Strain Name：C57BL/6Smoc-Vegfatm2(hVEGFA)Smoc
Strain State：Repository Live | Cat. NO.：NM-HU-2000028
Validation Data：Presence

The endogenous mouse Vegfa gene was replaced by human VEGFA gene. While hVEGFA(2)(Stock No.NM-HU-204984) mice function similarly to hVEGFA mice,for more detailed information please contact our technical advisor.

Mice

hSOST

Strain Name：C57BL/6Smoc-Sosttm1(hSOST)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-200251
Validation Data：Presence

The endogenous mice Sost gene was replaced by human SOST gene. While hSOST(2)(Stock No.NM-HU-215021) mice function similarly to hSOST mice, for more detailed information please contact our technical advisor.

Mice

hICOSL

Strain Name：C57BL/6Smoc-Icosltm1(hICOSLG) Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-00095
Validation Data：Presence

The endogenous mouse Icosl gene was replaced by human ICOSL gene . While hICOSL(2)(Stock No.NM-HU-2000068) mice function similarly to hICOSL mice,for more detailed information please contact our technical advisor.

Mice

hSIGLEC8

Strain Name：C57BL/6Smoc-Siglecetm1(hSIGLEC8)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-204983

The endogenous mice Siglece gene was replaced by human SIGLEC8 gene. While hSIGLEC8(2)(Stock No.NM-HU-210033) mice function similarly to hSIGLEC8 mice,for more detailed information please contact our technical advisor.

Mice

hICOS

Strain Name：C57BL/6Smoc-Icostm1(hICOS)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-00052
Validation Data：Presence

The endogenous mouse Icos gene was replaced by human ICOS gene. While hICOS(2)(Stock No.NM-HU-190030) mice function similarly to hICOS mice,for more detailed information please contact our technical advisor.

Mice

Lepr-g.G109052T

Strain Name：B6.129S-Leprtm1Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-KI-00001

A point mutation was introduced to exon 19 (c.109052 G>T) via a recombineering strategy. Homozygous mutants are hyperphagic, low-activity, poorly cold-adapted, sterile and have enhanced fat conversion.

Mice

KPC(2)

Strain Name：C57BL/6Smoc-Trp53tm7(R270H-flox)Krasem4(LSL-G12D)Tg(Pdx1-cre)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-KI-220014

Trp53-LSL-R270H, Kras-LSL-G12D were crossed with Pdx1-Cre-Tg to generate KPC mice. While KPC mice function similarly to KPC(2) mice, for more detailed information please contact our technical advisor.

Mice

BALB/c

Strain Name：BALB/cAnSmoc
Strain State：Repository Live | Cat. NO.：SM-003

BALB/c is one of the most widely used inbred lines in biomedical research, especially in immunology and infectious disease research. The incidence of breast tumors is about 10% to 20%. There is a certain number of ovarian, adrenal, pulmonary tumors, and leukemia that occurs. Lung cancer occurs in 26% of female mice and 29% of male mice. The incidence of leukemia is 12% in females and 10% in males. Blood pressure was the highest compared to other inbred mice and had spontaneous hypertension.

Mice

Slc6a4-Cre

Strain Name：C57BL/6Smoc-Slc6a4em1(iCre-pA)Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-KI-200115
Validation Data：Presence

A iCre-pA expression cassette was knocked into the Slc6a4 gene start codon site. When crossed with a strain carrying a gene flanked by loxP sites, the flanked gene will be removed in cells expressing Cre. The gene product has been involved in the neurological disorders such as addiction and depression.

Mice

Jak2-Flox-V617F

Strain Name：C57BL/6Smoc-Jak2tm1(Flox-V617F)Smoc
Strain State：Repository Live | Cat. NO.：NM-KI-210367

These mice carry a V617F conditional mutation of Jak2 gene. While Jak2-Flox-V617F(2)(Stock No.NM-KI-220009) mice function similarly to Jak2-flox-V617F mice, for more detailed information please contact our technical advisor.

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