Welcome to Advanced Search

Models

About 791 results
Mice

Paqr4-Flox

Strain Name：B6;129S-Paqr4tm2(flox)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-CKO-00069

These mice carry loxP sites flanking exons 2-3 of the progestin and adipoQ receptor family member IV gene. When crossed with a Cre recombinase-expressing strain, this strain is useful in eliminating tissue-specific conditional expression of the gene.

Mice

Etv1-CreERT2

Strain Name：C57BL/6Smoc-Etv1em1(CreERT2-SV40-pA)Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-KI-200105
Validation Data：Presence

A CreERT2 expression cassette was knocked into the Etv1 gene start codon site. ETV1 expression is enriched in fast conduction tissues of embryonic and adult mammalian hearts. And ETV1 expression is upregulated in the atrial tissue of patients with permanent atrial fibrillation. Etv-CreERT2 mice can be applied to heart disease research. ETV1 is also expressed in retinal ganglion cells of adult mice, and the mouse model can be used to study how retinal ganglion cells contribute to visual processing in the brain.

Mice

Prom1-CreERT2

Strain Name：C57BL/6Smoc-Prom1em1(CreERT2-PolyA)Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-KI-200169
Validation Data：Presence

A CreERT2-PolyA expression cassette was knocked into the Prom1 gene start codon site. Prom1 encodes a pentaspan transmembrane glycoprotein. The protein localizes to membrane protrusions and is often expressed on adult stem cells, where it is thought to function in maintaining stem cell properties by suppressing differentiation. When these Prom1-CreERT2 mice are bred with mice containing a loxP-flanked sequence of interest, tamoxifen-inducible, Cre-mediated recombination will result in deletion of the flanked sequences in Prom1 expressing cells.

Mice

Nkx2-1-CreERT2

Strain Name：C57BL/6Smoc-Nkx2-1em1(CreERT2-pA)Smoc
Strain State：Repository Live | Cat. NO.：NM-KI-200123
Validation Data：Presence

A CreERT2-pA expression cassette was knocked into the Nkx2-1 gene start codon site. Nkx2-1, a key molecule in lung development, is expressed in adult bronchial and alveolar type Ⅱ epithelial cells. Besides, Nkx2-1 expression as a prognostic marker is also been applied to lung cancer research including lung adenocarcinoma.

Mice

hPVRIG

Strain Name：C57BL/6Smoc-Pvrigtm1(hPVRIG)/Smoc
Strain State：Repository Live | Cat. NO.：NM-HU-210008
Validation Data：Presence

The endogenous mice Pvrig gene was replaced by human PVRIG gene While hPVRIG(2)(Stock No.NM-HU-215013) mice function similarly to hPVRIG mice, for more detailed information please contact our technical advisor.

Mice

hCTLA-4

Strain Name：C57BL/6Smoc-Ctla4tm1(hCTLA4) Smoc
Strain State：Repository Live | Cat. NO.：NM-HU-00014
Validation Data：Presence

The endogenous mouse Ctal4 gene was replaced by human CTLA4 gene. While hCTLA4(2)(Stock No.NM-HU-190038) mice function similarly to hCTLA4 mice,for more detailed information please contact our technical advisor.

Mice

hCD24

Strain Name：C57BL/6Smoc-Cd24atm1(hCD24)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-2000060
Validation Data：Presence

The endogenous mouse Cd24a gene was replaced by human CD24 gene. While hCD24(2)(Stock No.NM-HU-215025) mice function similarly to hCD24 mice, for more detailed information please contact our technical advisor.

Mice

hCD3E

Strain Name：C57BL/6Smoc-Cd3etm1(hCD3E) Smoc
Strain State：Repository Live | Cat. NO.：NM-HU-00114
Validation Data：Presence

The endogenous mouse Cd3e gene was replaced by human CD3E gene . While hCD3E(2)(Stock No.NM-HU-210023) mice function similarly to hCD3E mice,for more detailed information please contact our technical advisor.

Mice

hTIGIT

Strain Name：C57BL/6Smoc-Tigittm1(hTIGIT)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-00053
Validation Data：Presence

The endogenous mouse Tigit gene was replaced by human TIGIT gene. While hTIGIT(3)(Stock No.NM-HU-200244) mice function similarly to hTIGIT mice,for more detailed information please contact our technical advisor.

Mice

hCCR8

Strain Name：C57BL/6Smoc-Ccr8tm1(hCCR8) Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-190053
Validation Data：Presence

The endogenous mouse Ccr8 gene was replaced by human CCR8 gene. While hCCR8(2)(Stock No.NM-HU-2000054) mice function similarly to hCCR8 mice,for more detailed information please contact our technical advisor.

Email Back to top