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Mice

TIGRE-NF-kb-RE-Luc2P

Strain Name：C57BL/6Smoc-Igs7em1(2xINS-pA-pause site-NF-kb-RE-Luciferase-hPEST-SV40 poly(A)-pA-pause site-NF-kb-RE-Luciferase-hPEST-SV40 poly(A)-pA-pause site-NF-kb-RE-Luciferase-hPEST-SV40 poly(A)-2xINS)Smoc
Strain State：Developing | Cat. NO.：NM-KI-242923

The 2xINS-pA-pause site-NF-kb-RE-Luciferase-hPEST-SV40 poly(A)-pA-pause site-NF-kb-RE-Luciferase-hPEST-SV40 poly(A)-pA-pause site-NF-kb-RE-Luciferase-hPEST-SV40 poly(A)-2xINS expression cassette was knocked into the Tigre locus.

Mice

hHLA-A2.1/B2M(NMG)(2)

Strain Name：NOD.Cg-PrkdcscidIl2rgem1B2mem1(hB2M-linker-HLA-A*0201/H2-D1)Smoc
Strain State：Developing | Cat. NO.：NM-HU-241683

The endogenous mouse B2m gene was replaced by hB2M/HLA-A2.1/H2-D1 gene.

Mice

Cdkn2a-Luc-2A-tdTomato-2A-CreERT2(p16-Luc-2A-tdTomato-2A-CreERT2)

Strain Name：C57BL/6Smoc-Cdkn2aem(Luc-tdTomato-CreERT2)Smoc
Strain State：Repository Live | Cat. NO.：NM-KI-18039

A Luc-2A-tdTomato-2A-CreERT2-WPRE-pA cassette was fused in-frame with exon2 of p16INK4a transcript such that the exogenous proteins would be translated followed by the first 62aa of Cdkn2a.

Mice

Il1b-Luc-2A-EGFP

Strain Name：C57BL/6Smoc-Il1bem1(Luc-eGFP)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-KI-00010

A Luciferase-2A-EGFP-pA cassette was inserted at ATG site of mouse Il1b gene. The intrisic promoter drives the expression of reporter genes, which reflects the activity of Il1b.

Mice

Zbtb46-IRES-Cre

Strain Name：C57BL/6Smoc-Zbtb46em1(IRES-iCre)Smoc
Strain State：Repository Live | Cat. NO.：NM-KI-200096

A  IRES-iCre expression cassette was knocked into the Zbtb46 gene stop codon site. This strain carries a significant risk of reproductive system leakage. Avoid using homozygotes and female Cre mice. It is recommended to use male mice, as they have a lower probability of leakage. After mating, offspring should be genotyped and promptly checked for any occurrence of reproductive leakage.

Mice

R26-CAG-LSL-Luc-2A-EGFP

Strain Name：C57BL/6Smoc-Gt(ROSA)26Sorem1(CAG-LSL-Luciferase-2A-EGFP-wpre-polyA)Smoc
Strain State：Repository Live | Cat. NO.：NM-KI-190095

A CAG-LSL-Luciferase-2A-EGFP-wpre-polyA expression cassette was inserted at the Rosa26 locus site.

Mice

Shh-CreERT2

Strain Name：C57BL/6Smoc-Shhem1(CreERT2-WPRE-polyA)Smoc
Strain State：Repository Live | Cat. NO.：NM-KI-200145

A  CreERT2-WPRE-polyA expression cassette was knocked into the Shh gene start codon site. Expression of Shh-CreERT2 may be "leaky" at 1-month-old mice without tamoxifen.

Mice

Gp1ba-2A-Cre

Strain Name：C57BL/6Smoc-Gp1baem1(T2A-iCre)Smoc
Strain State：Repository Live | Cat. NO.：NM-KI-200172

A T2A-iCre expression cassette was knocked into the Gp1ba gene stop codon site.

Mice

Fos-CreERT2

Strain Name：C57BL/6Smoc-Fosem1(CreERT2-SV40-pA)Smoc
Strain State：Repository Live | Cat. NO.：NM-KI-200110

A CreERT2 expression cassette was knocked into the Fos gene start codon site.

Mice

Cd4-IRES-DTRGFP

Strain Name：C57BL/6Smoc-Cd4em5(IRES-DTREGFP)Smoc
Strain State：Repository Live | Cat. NO.：NM-KI-190121

A IRES-DTREGFP expression cassette was knocked into the Cd4 gene stop codon site.

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